Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Telmisartan
Drug ID BADD_D02147
Description Telmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 (AT1) receptors with high affinity, causing inhibition of the action of angiotensin II on vascular smooth muscle, ultimately leading to a reduction in arterial blood pressure. Recent studies suggest that telmisartan may also have PPAR-gamma agonistic properties that could potentially confer beneficial metabolic effects.
Indications and Usage Used alone or in combination with other classes of antihypertensives for the treatment of hypertension. Also used in the treatment of diabetic nephropathy in hypertensive patients with type 2 diabetes mellitus, as well as the treatment of congestive heart failure (only in patients who cannot tolerate ACE inhibitors).
Marketing Status Prescription
ATC Code C09CA07
DrugBank ID DB00966
KEGG ID D00627
MeSH ID D000077333
PubChem ID 65999
TTD Drug ID D0N6RF
NDC Product Code 68554-0049; 43547-283; 67877-484; 65862-868; 71335-0875; 65162-292; 72241-015; 65404-007; 62512-0040; 53104-7624; 65862-867; 46708-610; 71335-1723; 62332-088; 42571-226; 0378-2921; 62332-089; 62332-087; 65162-291; 65372-1146; 71209-049; 52562-009; 68462-199; 65162-293; 53746-291; 43547-284; 55545-0701; 72241-016; 0781-5374; 45865-836; 0597-0041; 70518-2572; 31722-803; 71335-1841; 13668-156; 42571-228; 57451-1206; 0781-5378; 53746-292; 12666-0010; 68071-2591; 50090-5489; 71052-679; 63629-5682; 43547-285; 62331-032; 67877-483; 71335-1428; 55111-095; 0378-2922; 71209-051; 72761-021; 72606-507; 50090-5490; 31722-804; 50370-0015; 67877-482; 68382-471; 52286-0024; 50090-5492; 68071-4937; 68382-473; 65862-869; 68462-200; 64552-4026; 31722-802; 65862-727; 68462-201; 0597-0039; 0378-2920; 65841-806; 68071-5178; 72606-506; 46708-864; 42291-792; 42291-791; 72969-100; 53746-293; 65841-805; 70518-3300; 13668-158; 65015-845; 13668-157; 63187-951; 68382-472; 46708-609; 64220-124; 72241-017; 71209-050; 42291-790; 0781-5372; 42571-227; 65841-804; 46708-608; 63629-7230; 17511-126; 72606-508; 0597-0040; 66039-895
Synonyms Telmisartan | 4'-((1,4'-Dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl)methyl)-(1,1'-biphenyl)-2-carboxylic acid | Pritor | BIBR 277 | BIBR-277 | Micardis
Chemical Information
Molecular Formula C33H30N4O2
CAS Registry Number 144701-48-4
SMILES CCCC1=NC2=C(N1CC3=CC=C(C=C3)C4=CC=CC=C4C(=O)O)C=C(C=C2C)C5=NC6=CC=CC=C6N5C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Clostridium difficile colitis11.02.02.004; 07.19.01.0040.000501%Not Available
Colitis07.08.01.0010.003199%
Colitis ischaemic24.04.08.012; 07.08.01.0040.001280%Not Available
Colon cancer16.13.01.001; 07.21.01.0010.000501%Not Available
Confusional state19.13.01.001; 17.02.03.0050.003839%
Conjunctivitis11.01.06.012; 06.04.01.002--
Constipation07.02.02.001--
Coordination abnormal17.02.02.0040.001280%Not Available
Coronary artery occlusion24.04.04.013; 02.02.01.0060.001920%Not Available
Cough22.02.03.0010.007679%
Cystitis11.01.14.001; 20.03.02.002--
Deafness04.02.01.0010.001280%Not Available
Death08.04.01.001--
Dehydration14.05.05.0010.008319%
Delirium19.13.02.0010.001280%
Dementia19.20.02.001; 17.03.01.0010.003199%Not Available
Depression19.15.01.001--
Dermatitis23.03.04.002--Not Available
Diabetes insipidus05.03.03.004; 14.05.07.0030.002560%Not Available
Diabetes mellitus14.06.01.001; 05.06.01.0010.002560%Not Available
Diabetes mellitus inadequate control14.06.01.004; 05.06.01.0040.001280%Not Available
Diarrhoea07.02.01.001--
Discomfort08.01.08.003--Not Available
Disorientation19.13.01.002; 17.02.05.0150.001920%Not Available
Disturbance in attention19.21.02.002; 17.03.03.0010.001280%
Dizziness17.02.05.003; 02.01.02.004; 24.06.02.0070.014718%
Drug eruption23.03.05.001; 10.01.01.005; 08.01.06.015--Not Available
Dry mouth07.06.01.002--
Dry skin23.03.03.001--
Dysgeusia17.02.07.003; 07.14.03.001--
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