Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Telbivudine
Drug ID BADD_D02145
Description Telbivudine is a synthetic thymidine nucleoside analog with specific activity against the hepatitis B virus. Telbivudine is orally administered, with good tolerance, lack of toxicity and no dose-limiting side effects.
Indications and Usage For the treatment of chronic hepatitis B in adult and adolescent patients ≥16 years of age with evidence of viral replication and either evidence of persistent elevations in serum aminotransferases (ALT or AST) or histologically active disease.
Marketing Status Discontinued
ATC Code J05AF11
DrugBank ID DB01265
KEGG ID D06675
MeSH ID D000077712
PubChem ID 159269
TTD Drug ID D0CL9S
NDC Product Code Not Available
Synonyms Telbivudine | 1-(2-Deoxy-beta-L-erythropentafuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione | beta-L-2'-Deoxythymidine | beta L 2' Deoxythymidine | Telbivudin | Tyzeka
Chemical Information
Molecular Formula C10H14N2O5
CAS Registry Number 3424-98-4
SMILES CC1=CN(C(=O)NC1=O)C2CC(C(O2)CO)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Abdominal distension07.01.04.001--
Abdominal pain07.01.05.002--
Abdominal pain lower07.01.05.010--Not Available
Abdominal pain upper07.01.05.003--
Alanine aminotransferase increased13.03.01.003--
Amylase increased13.05.01.009--
Arthralgia15.01.02.001--
Aspartate aminotransferase increased13.03.01.006--
Asthenia08.01.01.001--Not Available
Back pain15.03.04.005--
Blood creatine phosphokinase increased13.04.01.001--
Body temperature increased13.15.01.001--Not Available
Chest discomfort08.01.08.019; 02.02.02.009; 22.02.08.001--Not Available
Chest pain22.02.08.003; 08.01.08.002; 02.02.02.011--Not Available
Cough22.02.03.001--
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Discomfort08.01.08.003--Not Available
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Dysgeusia17.02.07.003; 07.14.03.001--
Dyspepsia07.01.02.001--
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014--Not Available
Flank pain15.03.04.003; 08.01.08.007; 20.02.03.006--
Frequent bowel movements07.02.04.002--Not Available
Gastritis07.08.02.001--
Gastrointestinal disorder07.11.01.001--Not Available
Gastrointestinal pain07.01.05.005--
Headache17.14.01.001--
The 1th Page    1 2 3 4    Next   Last    Total 4 Pages