Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Technetium tc-99m medronate
Drug ID BADD_D02129
Description Technetium (99mTc) medronic acid is a pharmaceutical product used in nuclear medicine imaging. It is composed of a technetium ion complexed with medronic acid, a type of bisphosphonate. Like other bisphosphonates used in the treatment of osteoporosis, medronic acid binds to the hydroxyapatite crystals within bone, and in this way localizes the drug to bone for delineation of areas of altered osteogenesis. Following intravenous injection, single photon emission computed tomography (SPECT) is performed to detect the gamma ray emmitted by the decay of Technetium-99m to Technetium-99.
Indications and Usage Technetium Tc 99m Medronate is indicated for use as a bone imaging agent to delineate areas of altered osteogenesis.
Marketing Status Prescription; Discontinued
ATC Code V09BA02
DrugBank ID DB09138
KEGG ID D02029
MeSH ID D013669
PubChem ID 9838324
TTD Drug ID D0B4KH
NDC Product Code Not Available
Synonyms Technetium Tc 99m Medronate | Tc-99 Medronate | Medronate, Tc-99 | Tc 99 Medronate | Technetium Methylene Diphosphonate | Diphosphonate, Technetium Methylene | Methylene Diphosphonate, Technetium | Technetium Tc 99m Methylenediphosphonate | 99mTc-Methylene Diphosphonate | 99mTc Methylene Diphosphonate | Diphosphonate, 99mTc-Methylene | 99mTc-MDP | Tc-99m MDP | Tc-99m Methylene Diphosphonate | Diphosphonate, Tc-99m Methylene | Methylene Diphosphonate, Tc-99m | Tc 99m Methylene Diphosphonate
Chemical Information
Molecular Formula CH2O6P2Tc
CAS Registry Number 121524-79-6
SMILES C(P(=O)([O-])[O-])P(=O)([O-])[O-].[Tc+4]
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Arrhythmia02.03.02.001--Not Available
Asthenia08.01.01.001--Not Available
Cardiac arrest02.03.04.001--
Chills15.05.03.016; 08.01.09.001--
Dizziness17.02.05.003; 02.01.02.004; 24.06.02.007--
Hypersensitivity10.01.03.003--
Hypotension24.06.03.002--
Nausea07.01.07.001--
Pruritus23.03.12.001--
Pyrexia08.05.02.003--
Rash23.03.13.001--Not Available
Vomiting07.01.07.003--
The 1th Page    1    Total 1 Pages