| Pharmaceutical Information |
| Drug Name |
Tavaborole |
| Drug ID |
BADD_D02119 |
| Description |
Tavaborale is a novel, boron-based topical antifungal medication for the treatment of onychomycosis, a fungal infection of the nail and nail bed due to *Trichophyton rubrum* or *Trichophyton mentagrophytes* infection. Tavaborole functions by inhibiting Leucyl-tRNA synthetase, or LeuRS, an essential fungal enzyme required for protein synthesis and for the catalysis of ATP-dependent ligation of L-leucine to tRNA(Leu). |
| Indications and Usage |
Indicated for the treatment of onychomycosis (a fungal infection) of the toenails due to Trichophyton rubrum or Trichophyton mentagrophytes. |
| Marketing Status |
Prescription |
| ATC Code |
D01AE24 |
| DrugBank ID |
DB09041
|
| KEGG ID |
D10169
|
| MeSH ID |
C512998
|
| PubChem ID |
11499245
|
| TTD Drug ID |
D05VGL
|
| NDC Product Code |
10337-905; 69766-037; 69575-4018; 69097-686; 51672-1397; 58175-0614; 69238-1657; 66039-932; 50909-1702; 62332-467; 71589-010; 0574-0157; 69037-0034; 51862-690; 63629-8704; 68180-958 |
| Synonyms |
tavaborole | 5-fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole | AN 2690 | AN2690 | AN-2690 | Kerydin |
|
| Chemical Information |
| Molecular Formula |
C7H6BFO2 |
| CAS Registry Number |
174671-46-6 |
| SMILES |
B1(C2=C(CO1)C=C(C=C2)F)O |
| Chemical Structure |
|
|
| ADR Related Proteins Induced by Drug |
| ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
| Not Available | Not Available | Not Available | Not Available | Not Available |
|
| ADRs Induced by Drug |
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