Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Talc
Drug ID BADD_D02109
Description Talc is a mineral composed primarily of magnesium, silicon and oxygen. It is a substance often found in cosmetic and personal hygiene products including baby powder, adult body powders and facial powders. Talc helps absorb moisture, freshen materials, and reduce friction to prevent rashes. Although talc has been widely used for decades, lawsuits that have come to the surface claim serious health complications linked to its use. In fact, recent studies have reported that talc increases the risk of ovarian and endometrial cancers by approximately 30 percent.
Indications and Usage Absorbing excess oil in hair, Freshening clothes and other materials.
Marketing Status Prescription
ATC Code Not Available
DrugBank ID DB09511
KEGG ID D01084
MeSH ID D013627
PubChem ID 16211421
TTD Drug ID Not Available
NDC Product Code 62327-333; 71161-150; 71161-148; 71161-149; 51552-0219; 52862-010; 0363-0901; 62327-222; 62327-444
Synonyms Talc | Talcum Powder
Chemical Information
Molecular Formula H2Mg3O12Si4
CAS Registry Number 14807-96-6
SMILES O.O=[Mg].O=[Mg].O=[Mg].O=[Si]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Acute respiratory distress syndrome22.01.03.001--
Cardiac arrest02.03.04.001--
Dyspnoea22.02.01.004; 02.01.03.002--
Empyema11.01.08.020--Not Available
Haemoptysis22.02.03.004; 02.01.02.006; 24.07.01.006--Not Available
Hypotension24.06.03.002--
Hypovolaemia14.05.05.002--Not Available
Hypoxia22.02.02.003--
Myocardial infarction24.04.04.009; 02.02.02.007--
Pain08.01.08.004--
Pneumonia11.01.09.003; 22.07.01.003--Not Available
Pulmonary embolism24.01.06.001; 22.06.02.001--Not Available
Pulmonary oedema22.01.03.003; 02.05.02.003--
Subcutaneous emphysema23.07.04.006; 12.02.06.002--
Tachycardia02.03.02.007--Not Available
Application site infection12.07.01.012; 11.01.08.012; 08.02.01.015--Not Available
Bronchopleural fistula22.05.03.001--
Haemorrhage24.07.01.002--Not Available
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