Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Suprofen
Drug ID BADD_D02102
Description An ibuprofen-type anti-inflammatory analgesic and antipyretic. It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic. It is no longer approved for use in the United States.
Indications and Usage Used as eye drops to inhibit the miosis (pupil constriction) that may occur during ocular surgery.
Marketing Status Discontinued
ATC Code M01AE07
DrugBank ID DB00870
KEGG ID D00452
MeSH ID D013496
PubChem ID 5359
TTD Drug ID D07BPS
NDC Product Code Not Available
Synonyms Suprofen | TN-762 | TN 762 | TN762 | R-25061 | R 25061 | R25061
Chemical Information
Molecular Formula C14H12O3S
CAS Registry Number 40828-46-4
SMILES CC(C1=CC=C(C=C1)C(=O)C2=CC=CS2)C(=O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Burning sensation08.01.09.029; 17.02.06.001--Not Available
Conjunctival oedema06.04.01.001--Not Available
Discomfort08.01.08.003--Not Available
Erythema23.03.06.001--Not Available
Haemoglobin13.01.05.018--Not Available
Haemorrhagic disorder24.07.01.021; 01.01.03.004--Not Available
Hypersensitivity10.01.03.003--
Iritis10.02.01.022; 06.04.03.002--Not Available
Pain08.01.08.004--
Photophobia17.17.02.006; 06.01.01.004--
Pruritus23.03.12.001--
Punctate keratitis06.04.02.003--Not Available
Skin irritation23.03.04.009--Not Available
Haemorrhage24.07.01.002--Not Available
Haemorrhagic diathesis24.07.01.020; 01.01.03.003--Not Available
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