Pharmaceutical Information |
Drug Name |
Streptomycin |
Drug ID |
BADD_D02071 |
Description |
Streptomycin, an antibiotic derived from _Streptomyces griseus_, was the first aminoglycoside to be discovered and used in practice in the 1940s.[A233325,A233390] Selman Waksman and eventually Albert Schatz were recognized with the Nobel Prize in Medicine for their discovery of streptomycin and its antibacterial activity.[A233325,A232294] Although streptomycin was the first antibiotic determined to be effective against mycobacterium tuberculosis, it has fallen out of favor due to resistance and is now primarily used as adjunctive treatment in cases of multi-drug resistant tuberculosis.[A233325] |
Indications and Usage |
For the treatment of tuberculosis. May also be used in combination with other drugs to treat tularemia (Francisella tularensis), plague (Yersia pestis), severe M. avium complex, brucellosis, and enterococcal endocarditis (e.g. E. faecalis, E. faecium). |
Marketing Status |
Prescription; Discontinued |
ATC Code |
A07AA04; J01GA01 |
DrugBank ID |
DB01082
|
KEGG ID |
D08531
|
MeSH ID |
D013307
|
PubChem ID |
19649
|
TTD Drug ID |
D0N0EQ
|
NDC Product Code |
39822-0706 |
Synonyms |
Streptomycin | Streptomycine Panpharma | Streptomycin Grünenthal | Estreptomicina CEPA | Strepto-Hefa | Strepto Hefa | Estreptomicina Clariana | Estreptomicina Normon | Strepto-Fatol | Strepto Fatol | Streptomycin Sulfate | Streptomycin Sulfate (2:3) Salt | Streptomycin Sulphate |
|
Chemical Information |
Molecular Formula |
C21H39N7O12 |
CAS Registry Number |
57-92-1 |
SMILES |
CC1C(C(C(O1)OC2C(C(C(C(C2O)O)N=C(N)N)O)N=C(N)N)OC3C(C(C(C(O3)CO)O)O)NC)(C=O)O |
Chemical Structure |
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|
ADR Related Proteins Induced by Drug |
ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
Not Available | Not Available | Not Available | Not Available | Not Available |
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ADRs Induced by Drug |
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