Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Sertraline hydrochloride
Drug ID BADD_D02011
Description Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as [Citalopram] and [Fluoxetine]. Despite marked structural differences between compounds in this drug class, SSRIs exert similar pharmacological effects. Several weeks of therapy with sertraline may be required before beneficial effects are noticed. Sertraline displays enhanced safety or tolerability than other classes of antidepressants, which frequently cause high levels of drowsiness, dizziness, blurred vision, and other undesirable effects.[A1846,A187075,T28]
Indications and Usage It may be used for premature ejaculation and vascular headaches as off-label indications.
Marketing Status Prescription; Discontinued
ATC Code N06AB06
DrugBank ID DB01104
KEGG ID D00825
MeSH ID D020280
PubChem ID 63009
TTD Drug ID D0K0TC
NDC Product Code 16714-612; 55700-340; 43602-979; 53869-4900; 0049-4960; 68071-4029; 71093-129; 65841-044; 65841-043; 50090-2080; 72865-205; 45865-518; 59762-0067; 71205-343; 65015-821; 43602-980; 61919-345; 46144-108; 55700-910; 68071-3071; 53002-3192; 70518-0094; 0049-4900; 65862-013; 70518-1350; 63187-859; 72789-088; 68071-4658; 65977-0056; 68071-3146; 64980-409; 61919-014; 43353-970; 53002-1507; 50090-3203; 68071-4993; 68788-8109; 71205-028; 31722-147; 43063-855; 65841-045; 51655-265; 68071-1911; 60760-737; 71205-455; 71205-205; 68071-4973; 53104-7590; 50436-0217; 53808-1127; 65862-222; 50090-2976; 50436-0216; 16729-216; 60687-242; 53002-1192; 70518-3145; 43353-447; 68071-2496; 67046-559; 55700-948; 65862-011; 60760-738; 51655-345; 71610-433; 68788-6429; 68788-7928; 72189-122; 60687-253; 65862-012; 61919-086; 42708-124; 71610-106; 53002-4215; 43063-033; 71093-143; 51655-173; 63629-8774; 63629-8127; 70934-192; 71335-0328; 60760-091; 69097-833; 71335-0210; 65977-0002; 53002-3215; 65862-224; 68071-4462; 55700-362; 71335-0415; 72865-206; 68071-3309; 55289-409; 50090-3945; 31722-146; 71093-130; 67046-554; 50090-3153; 71335-0808; 53869-4960; 68071-1318; 55154-4687; 58118-0834; 53002-2507; 55154-4692; 62350-0043; 70934-190; 71610-435; 71335-0403; 53104-7578; 16729-217; 43063-754; 68071-4370; 70518-1748; 16714-613; 68788-6835; 72789-013; 70518-2448; 70934-169; 71093-131; 0049-4910; 70518-1913; 68645-521; 69097-834; 72865-207; 53869-4910; 63187-795; 31722-145; 60760-612; 43602-981; 16714-601; 71205-047; 50090-2609; 71335-1078; 77777-108; 71335-0718; 16729-215; 52427-672; 68071-1317; 71335-0510; 0143-9655; 70518-2812; 68788-6437; 0049-0050; 68071-4750; 50090-3947; 69097-835; 63187-767; 60687-231; 50436-0215; 71335-0896; 42708-092; 55111-968; 70518-2706; 53002-1215; 72789-092; 52427-664; 16714-611; 68645-523; 55700-562; 68071-4494; 68645-522
Synonyms Sertraline | Zoloft | Altruline | Lustral | Apo-Sertraline | Apo Sertraline | Aremis | Besitran | Sealdin | Gladem | Novo-Sertraline | Novo Sertraline | ratio-Sertraline | ratio Sertraline | Rhoxal-sertraline | Rhoxal sertraline | Sertraline Hydrochloride | Hydrochloride, Sertraline | Sertraline Hydrochloride (1S-cis)-Isomer | Gen-Sertraline | Gen Sertraline
Chemical Information
Molecular Formula C17H18Cl3N
CAS Registry Number 79559-97-0
SMILES CNC1CCC(C2=CC=CC=C12)C3=CC(=C(C=C3)Cl)Cl.Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Poisoning and toxicityCytochrome P450 2D6P10635T57392Not Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Anxiety disorder19.06.01.002--Not Available
Female sexual dysfunction21.03.02.004; 19.08.05.001--Not Available
Male sexual dysfunction21.03.02.012; 19.08.05.003--Not Available
Vasodilation procedure25.03.01.001--Not Available
Muscle relaxant therapy25.16.01.001--Not Available
Disturbance in sexual arousal19.08.04.003--Not Available
Cerebral vasoconstriction24.04.06.025; 17.08.02.012--Not Available
Angiopathy24.03.02.007--Not Available
Blood alkaline phosphatase increased13.04.02.004--
Adhesion08.01.03.048--Not Available
Urine output increased13.13.03.002--Not Available
Hot flush24.03.01.005; 21.02.02.001; 08.01.03.027--
Benign neoplasm16.02.02.007--Not Available
Breast disorder21.05.04.004--Not Available
Cardiac disorder02.01.01.003--Not Available
Connective tissue disorder15.06.01.006--Not Available
Malnutrition14.03.02.004--Not Available
Mediastinal disorder22.09.03.001--Not Available
Mental disorder19.07.01.002--Not Available
Decreased appetite14.03.01.005; 08.01.09.028--
Erectile dysfunction21.03.01.007; 19.08.04.001--
Ill-defined disorder08.01.03.049--Not Available
Inner ear disorder04.04.02.002--Not Available
Lacrimal disorder06.08.02.005--Not Available
Blood disorder01.05.01.004--Not Available
Autonomic neuropathy17.05.01.009--Not Available
Psychotic disorder19.03.01.002--
Hepatobiliary disease09.01.08.003--Not Available
Respiratory tract infection22.07.07.001; 11.01.08.017--Not Available
Cystitis noninfective20.03.02.001--
The 13th Page    First    Pre   13 14    Next   Last    Total 14 Pages