Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Secobarbital
Drug ID BADD_D01997
Description Secobarbital (marketed by Eli Lilly and Company under the brand names Seconal and Tuinal) is a barbiturate derivative drug with anaesthetic, anticonvulsant, sedative and hypnotic properties. It is commonly known as quinalbarbitone in the United Kingdom.
Indications and Usage For the Short-term treatment of intractable insomnia for patients habituated to barbiturates
Marketing Status Prescription; Discontinued
ATC Code N05CA06
DrugBank ID DB00418
KEGG ID D00430
MeSH ID D012631
PubChem ID 5193
TTD Drug ID D00SJE
NDC Product Code Not Available
Synonyms Secobarbital | Meballymal | Quinalbarbitone | Sebar | Seconal Sodium | Seconal | Secobarbital Sodium | Sodium, Secobarbital
Chemical Information
Molecular Formula C12H18N2O3
CAS Registry Number 76-73-3
SMILES CCCC(C)C1(C(=O)NC(=O)NC1=O)CC=C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Agitation19.06.02.001; 17.02.05.012--
Anaemia megaloblastic01.03.02.003; 14.12.01.003--Not Available
Angioedema23.04.01.001; 10.01.05.009--Not Available
Anxiety19.06.02.002--
Apnoea22.02.01.001--
Ataxia17.02.02.001; 08.01.02.004--
Body temperature increased13.15.01.001--Not Available
Bradycardia02.03.02.002--Not Available
Confusional state19.13.01.001; 17.02.03.005--
Constipation07.02.02.001--
Depressed level of consciousness17.02.04.002--
Dermatitis23.03.04.002--Not Available
Dermatitis exfoliative23.03.07.001; 10.01.01.004--
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Feeling abnormal08.01.09.014--Not Available
Hallucination19.10.02.002--
Headache17.14.01.001--
Hepatocellular injury09.01.07.008--Not Available
Hyperkinesia17.01.02.008--Not Available
Hypersensitivity10.01.03.003--
Hypotension24.06.03.002--
Hypoventilation22.02.01.007--Not Available
Hypoxia22.02.02.003--
Injection site reaction12.07.03.015; 08.02.03.014--
Loss of consciousness17.02.04.004--Not Available
Mental disability26.01.01.001--Not Available
Nausea07.01.07.001--
Nervousness19.06.02.003--Not Available
Nightmare19.02.03.003--Not Available
Rash23.03.13.001--Not Available
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