Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Sargramostim
Drug ID BADD_D01990
Description Sargramostim is a human recombinant granulocyte macrophage colony-stimulating factor (GM-CSF) expressed in yeast. It is a glycoprotein that is 127 residues. Substitution of Leu23 leads to a difference from native protein.
Indications and Usage For the treatment of cancer and bone marrow transplant
Marketing Status Prescription
ATC Code L03AA09
DrugBank ID DB00020
KEGG ID D05803
MeSH ID C081222
PubChem ID Not Available
TTD Drug ID D0XT5Y
NDC Product Code 71837-5843
Synonyms sargramostim | 23-L-leucine-colony-stimulating factor 2 (human clone pHG25 protein moiety) | Leukine | Prokine
Chemical Information
Molecular Formula Not Available
CAS Registry Number 123774-72-1
SMILES Not Available
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Pyrexia08.05.02.003--
Rash23.03.13.001--Not Available
Rhinitis22.07.03.006; 11.01.13.004--
Sensory disturbance17.02.07.006--Not Available
Sepsis11.01.11.003--
Stomatitis07.05.06.005--
Thrombocytopenia01.08.01.002--Not Available
Urinary tract disorder20.08.01.001--Not Available
Vomiting07.01.07.003--
Weight decreased13.15.01.005--
Weight increased13.15.01.006--
Haemorrhage24.07.01.002--Not Available
Metabolic disorder14.11.01.001--Not Available
Blood alkaline phosphatase increased13.04.02.004--
Neurological symptom17.02.05.010--Not Available
Decreased appetite14.03.01.005; 08.01.09.028--
Blood disorder01.05.01.004--Not Available
Renal impairment20.01.03.010--Not Available
Neuropsychological test abnormal13.07.06.001--Not Available
Liver injury12.01.02.003; 09.01.07.022--Not Available
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