Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Rufinamide
Drug ID BADD_D01977
Description Rufinamide is a triazole derivative and an anticonvulsant medication to treat seizure disorders like Lennox-Gastuat syndrome, a form of childhood epilepsy. Clinical trials suggest its efficacy in the treatment of partial seizures.
Indications and Usage Adjunct therapy for treatment of seizures associated with Lennox-Gastaut syndrome.
Marketing Status Prescription; Discontinued
ATC Code N03AF03
DrugBank ID DB06201
KEGG ID D05775
MeSH ID C079703
PubChem ID 129228
TTD Drug ID D0MD2L
NDC Product Code 66039-881; 51148-009; 51148-010; 46438-0662; 68462-713; 0378-2330; 31722-598; 0054-0426; 66005-0037; 69766-050; 51148-008; 69452-223; 0378-2331; 31722-599; 65977-0068; 14501-0058; 62856-584; 0054-0425; 46438-0661; 68462-714; 50923-0614; 62856-582; 62856-583; 67877-673; 0054-0528
Synonyms rufinamide | 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxamide | CGP 33101 | CGP-33101 | Inovelon
Chemical Information
Molecular Formula C10H8F2N4O
CAS Registry Number 106308-44-5
SMILES C1=CC(=C(C(=C1)F)CN2C=C(N=N2)C(=O)N)F
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Gait disturbance17.02.05.016; 08.01.02.002--
Gastrointestinal disorder07.11.01.001--Not Available
Haematuria24.07.01.047; 20.02.01.006--
Head injury12.01.09.003--Not Available
Headache17.14.01.001--
Hypersensitivity10.01.03.003--
Immune system disorder10.02.01.001--Not Available
Incontinence20.02.02.004; 17.05.01.006; 07.01.06.011--Not Available
Increased appetite14.03.01.003; 08.01.09.027--Not Available
Infection11.01.08.002--Not Available
Influenza11.05.03.001; 22.07.02.001--Not Available
Insomnia19.02.01.002; 17.15.03.002--
Iron deficiency anaemia14.13.02.001; 01.03.01.002--Not Available
Leukopenia01.02.02.001--Not Available
Lymphadenopathy01.09.01.002--Not Available
Nasopharyngitis22.07.03.002; 11.01.13.002--Not Available
Nausea07.01.07.001--
Nephrolithiasis20.04.01.002--
Nervous system disorder17.02.10.001--Not Available
Neutropenia01.02.03.004--Not Available
Nocturia20.02.03.001--Not Available
Nystagmus17.02.02.006; 06.05.02.006--
Oligomenorrhoea05.05.01.011; 21.01.02.004--Not Available
Pneumonia22.07.01.003; 11.01.09.003--Not Available
Pollakiuria20.02.02.007--
Polyuria20.02.03.002--Not Available
Pruritus23.03.12.001--
Psychomotor hyperactivity19.11.02.003; 17.01.02.011--Not Available
Rash23.03.13.001--Not Available
Rhinitis22.07.03.006; 11.01.13.004--
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