Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Rizatriptan benzoate
Drug ID BADD_D01958
Description Rizatriptan is a triptan drug used for the treatment of migraine headaches. It is a selective 5-hydroxytryptamine1 receptor subtype agonist.
Indications and Usage For treatment of acute migraine attacks with or without aura.
Marketing Status Prescription; Discontinued
ATC Code N02CC04
DrugBank ID DB00953
KEGG ID D00675
MeSH ID C093622
PubChem ID 77997
TTD Drug ID D0S9MU
NDC Product Code 51991-362; 64220-995; 70518-2957; 50090-3343; 50090-3921; 71335-1283; 63629-7433; 71335-0810; 43817-133; 68462-465; 29300-269; 71205-644; 70518-0509; 59746-415; 65862-625; 67877-262; 71335-1257; 57237-087; 51991-355; 68462-467; 69097-866; 63629-8256; 65862-626; 53747-043; 72189-258; 50090-4619; 65862-600; 43817-135; 69452-157; 71335-1172; 71335-1577; 69097-865; 51991-354; 65862-599; 72189-316; 55111-092; 78206-142; 71205-398; 0378-1403; 65372-1147; 69452-156; 55700-958; 67835-5016; 45865-825; 33342-093; 68462-468; 71335-1346; 57237-088; 53002-3713; 61919-656; 65015-653; 71205-557; 68462-466; 66039-835; 29300-268; 71335-1819; 67877-261; 51991-363; 59746-414; 64567-0013; 57237-085; 57237-086; 0093-7471; 53104-7580; 63187-563; 14593-872; 50090-3367; 72189-126; 29300-317; 33342-094; 0378-1404; 55700-942; 61919-394; 29300-316; 59746-446; 59746-445; 0093-7472; 78206-143; 71335-1912; 71335-1149; 64220-996; 53002-1713; 65862-578; 63629-8122; 71335-2031
Synonyms rizatriptan | N,N-dimethyl-2-(5-(1,2,4-triazol-1-ylmethyl)-1H-indole-3-yl)ethylamine | rizatriptan benzoate | MK 0462 | MK-0462 | MK-462 | MK 462 | L 705,126 | L-705,126 | L-705126 | L 705126 | Maxalt
Chemical Information
Molecular Formula C22H25N5O2
CAS Registry Number 145202-66-0
SMILES CN(C)CCC1=CNC2=C1C=C(C=C2)CN3C=NC=N3.C1=CC=C(C=C1)C(=O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Peripheral coldness08.01.09.010; 24.04.03.006--Not Available
Pharyngeal oedema10.01.05.016; 23.04.01.016; 22.04.05.003--Not Available
Presyncope24.06.02.010; 17.02.05.009; 02.01.02.007--
Pruritus23.03.12.001--
Rash23.03.13.001--Not Available
Seizure17.12.03.001--
Serotonin syndrome17.05.02.004; 15.05.04.016; 12.03.01.041--Not Available
Shock24.06.02.002--Not Available
Somnolence19.02.05.003; 17.02.04.006--
Swelling08.01.03.015--Not Available
Swollen tongue07.14.02.003; 23.04.01.014; 10.01.05.015--Not Available
Syncope24.06.02.012; 17.02.04.008; 02.01.02.008--
Tachycardia02.03.02.007--Not Available
Tension19.06.02.005--Not Available
Thirst08.01.09.021; 14.03.02.007--Not Available
Throat tightness22.02.05.015; 19.01.02.005--Not Available
Tinnitus04.04.01.002; 17.04.07.004--
Tongue oedema23.04.01.009; 10.01.05.008; 07.14.02.007--Not Available
Toxic epidermal necrolysis10.01.01.006; 23.03.01.008; 12.03.01.015; 11.07.01.006--
Tremor17.01.06.002--
Urticaria23.04.02.001; 10.01.06.001--
Vertigo17.02.12.002; 04.04.01.003--
Vision blurred17.17.01.010; 06.02.06.007--
Vomiting07.01.07.003--
Wheezing22.03.01.009--
Hypoacusis04.02.01.006--
Muscle tightness15.05.03.007--Not Available
Musculoskeletal stiffness15.03.01.005--Not Available
Musculoskeletal discomfort15.03.04.001--Not Available
Angiopathy24.03.02.007--Not Available
The 3th Page    First    Pre   3 4    Next   Last    Total 4 Pages