Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Rizatriptan
Drug ID BADD_D01957
Description Rizatriptan is a triptan drug used for the treatment of migraine headaches. It is a selective 5-hydroxytryptamine1 receptor subtype agonist.
Indications and Usage For treatment of acute migraine attacks with or without aura.
Marketing Status Prescription; Discontinued
ATC Code N02CC04
DrugBank ID DB00953
KEGG ID D08485
MeSH ID C093622
PubChem ID 5078
TTD Drug ID D0S9MU
NDC Product Code 63850-7138; 33342-087; 33342-088; 62938-0021; 62938-0022; 62938-0020; 63850-7119; 71335-1352; 62938-0019; 65977-0067
Synonyms rizatriptan | N,N-dimethyl-2-(5-(1,2,4-triazol-1-ylmethyl)-1H-indole-3-yl)ethylamine | rizatriptan benzoate | MK 0462 | MK-0462 | MK-462 | MK 462 | L 705,126 | L-705,126 | L-705126 | L 705126 | Maxalt
Chemical Information
Molecular Formula C15H19N5
CAS Registry Number 144034-80-0
SMILES CN(C)CCC1=CNC2=C1C=C(C=C2)CN3C=NC=N3
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Temperature intolerance08.01.09.022--Not Available
Urine output increased13.13.03.002--Not Available
Hot flush21.02.02.001; 08.01.03.027; 24.03.01.005--
Ischaemia24.04.02.004--Not Available
Ischaemic stroke24.04.06.010; 17.08.01.0180.000691%Not Available
Mental disorder19.07.01.002--Not Available
Cardiac valve disease02.07.02.0010.001382%Not Available
Decreased appetite14.03.01.005; 08.01.09.028--
Inner ear disorder04.04.02.002--Not Available
Drug intolerance08.06.01.0130.000691%Not Available
Sinus disorder22.04.06.002--
Treatment failure08.06.01.0170.000180%Not Available
Regurgitation07.01.07.004--Not Available
Medication overuse headache17.14.01.015; 08.06.02.015--Not Available
Reversible cerebral vasoconstriction syndrome24.04.06.026; 18.06.01.004; 17.08.02.0140.001382%Not Available
Depersonalisation/derealisation disorder19.14.01.004--Not Available
Congenital pulmonary valve atresia03.07.05.009; 02.07.04.0030.000691%Not Available
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