Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Rizatriptan
Drug ID BADD_D01957
Description Rizatriptan is a triptan drug used for the treatment of migraine headaches. It is a selective 5-hydroxytryptamine1 receptor subtype agonist.
Indications and Usage For treatment of acute migraine attacks with or without aura.
Marketing Status Prescription; Discontinued
ATC Code N02CC04
DrugBank ID DB00953
KEGG ID D08485
MeSH ID C093622
PubChem ID 5078
TTD Drug ID D0S9MU
NDC Product Code 63850-7138; 33342-087; 33342-088; 62938-0021; 62938-0022; 62938-0020; 63850-7119; 71335-1352; 62938-0019; 65977-0067
Synonyms rizatriptan | N,N-dimethyl-2-(5-(1,2,4-triazol-1-ylmethyl)-1H-indole-3-yl)ethylamine | rizatriptan benzoate | MK 0462 | MK-0462 | MK-462 | MK 462 | L 705,126 | L-705,126 | L-705126 | L 705126 | Maxalt
Chemical Information
Molecular Formula C15H19N5
CAS Registry Number 144034-80-0
SMILES CN(C)CCC1=CNC2=C1C=C(C=C2)CN3C=NC=N3
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Palpitations02.01.02.0030.002073%
Paraesthesia17.02.06.0050.001036%
Paralysis17.01.04.004--Not Available
Parosmia22.04.03.007; 17.04.04.002--Not Available
Periarthritis15.01.08.0050.001727%Not Available
Peripheral coldness24.04.03.006; 08.01.09.010--Not Available
Peripheral ischaemia24.04.03.0020.000691%
Pharyngeal oedema22.04.05.003; 23.04.01.016; 10.01.05.016--Not Available
Pharyngitis22.07.03.004; 11.01.13.003; 07.05.07.004--
Photophobia17.17.02.006; 06.01.01.004--
Photopsia17.17.01.006; 06.02.06.004--
Photosensitivity reaction23.03.09.003--
Pollakiuria20.02.02.007--
Polyuria20.02.03.002--Not Available
Presyncope24.06.02.010; 17.02.05.009; 02.01.02.007--
Prinzmetal angina24.04.04.015; 02.02.02.019--Not Available
Pruritus23.03.12.001--
Rash23.03.13.001--Not Available
Renal infarct24.04.11.003; 20.01.07.0080.001036%Not Available
Respiration abnormal22.02.08.0110.000691%Not Available
Rhinorrhoea22.02.05.010--
Seizure17.12.03.001--
Serotonin syndrome17.05.02.004; 15.05.04.016; 12.03.01.041--Not Available
Shock24.06.02.002--Not Available
Sinusitis22.07.03.007; 11.01.13.0050.000691%
Sleep disorder19.02.04.0010.000691%Not Available
Sneezing22.02.05.011--
Somnolence19.02.05.003; 17.02.04.0060.002073%
Suicide attempt19.12.01.0040.000691%
Swelling08.01.03.015--Not Available
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