Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Rizatriptan
Drug ID BADD_D01957
Description Rizatriptan is a triptan drug used for the treatment of migraine headaches. It is a selective 5-hydroxytryptamine1 receptor subtype agonist.
Indications and Usage For treatment of acute migraine attacks with or without aura.
Marketing Status Prescription; Discontinued
ATC Code N02CC04
DrugBank ID DB00953
KEGG ID D08485
MeSH ID C093622
PubChem ID 5078
TTD Drug ID D0S9MU
NDC Product Code 63850-7138; 33342-087; 33342-088; 62938-0021; 62938-0022; 62938-0020; 63850-7119; 71335-1352; 62938-0019; 65977-0067
Synonyms rizatriptan | N,N-dimethyl-2-(5-(1,2,4-triazol-1-ylmethyl)-1H-indole-3-yl)ethylamine | rizatriptan benzoate | MK 0462 | MK-0462 | MK-462 | MK 462 | L 705,126 | L-705,126 | L-705126 | L 705126 | Maxalt
Chemical Information
Molecular Formula C15H19N5
CAS Registry Number 144034-80-0
SMILES CN(C)CCC1=CNC2=C1C=C(C=C2)CN3C=NC=N3
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Hypoaesthesia17.02.06.023--Not Available
Hyporeflexia17.02.01.003--
Increased appetite14.03.01.003; 08.01.09.027--Not Available
Insomnia19.02.01.002; 17.15.03.0020.000691%
Irritability19.04.02.013; 08.01.03.0110.000691%
Joint swelling15.01.02.0040.000691%Not Available
Lacrimation increased06.08.02.004--
Loss of consciousness17.02.04.004--Not Available
Lower respiratory tract infection22.07.01.002; 11.01.09.0020.000691%Not Available
Malaise08.01.01.0030.002418%
Memory impairment19.20.01.003; 17.03.02.003--
Menopausal symptoms21.02.02.002--Not Available
Menstrual disorder21.01.01.004--Not Available
Migraine24.03.05.003; 17.14.02.0010.009674%Not Available
Migraine with aura17.14.02.002; 24.03.05.0050.000691%Not Available
Muscle spasms15.05.03.004--
Muscular weakness17.05.03.005; 15.05.06.001--
Musculoskeletal pain15.03.04.007--
Myalgia15.05.02.0010.000691%
Myocardial infarction24.04.04.009; 02.02.02.0070.000270%
Myocardial ischaemia24.04.04.010; 02.02.02.008--Not Available
Nasal dryness22.04.03.002--Not Available
Nasopharyngitis22.07.03.002; 11.01.13.002--Not Available
Nausea07.01.07.0010.012092%
Nervous system disorder17.02.10.001--Not Available
Nervousness19.06.02.003--Not Available
Oedema14.05.06.010; 08.01.07.006--Not Available
Osteoarthritis15.01.04.001--Not Available
Pain08.01.08.0040.001727%
Pain in jaw15.02.01.0030.000691%Not Available
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