Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Risedronic acid
Drug ID BADD_D01950
Description Risedronic acid is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label][A959].
Indications and Usage Risedronic acid is indicated for the treatment of osteoperosis in men, treatment of Paget's disease, treatment and prevention of osteoperosis in postmenopausal women, and treatment and prevention of glucocorticoid-induced osteoperosis[FDA Label].
Marketing Status approved; investigational
ATC Code M05BA07
DrugBank ID DB00884
KEGG ID D08484
MeSH ID D000068296
PubChem ID 5245
TTD Drug ID D0PA5S
NDC Product Code Not Available
UNII KM2Z91756Z
Synonyms Risedronic Acid | 1-Hydroxy-2-(3-pyridyl)ethylidene diphosphonate | Atelvia | Risedronate Sodium | 2-(3-pyridinyl)-1-hydroxyethylidene-bisphosphonate | 2-(3-pyridinyl)-1-hydroxyethylidenebisphosphonate | Risedronic Acid, Monosodium Salt | Actonel | Risedronate | Bisphosphonate Risedronate Sodium | Risedronate Sodium, Bisphosphonate | Sodium, Bisphosphonate Risedronate
Chemical Information
Molecular Formula C7H11NO7P2
CAS Registry Number 105462-24-6
SMILES C1=CC(=CN=C1)CC(O)(P(=O)(O)O)P(=O)(O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Osteoarthritis15.01.04.001--Not Available
Osteonecrosis24.04.05.004; 15.02.04.007--
Osteoporosis15.02.03.002; 14.04.04.002--
Osteoporotic fracture15.08.02.007; 12.04.02.005; 14.04.04.007--Not Available
Otitis media11.01.05.004; 04.05.01.001--
Pain08.01.08.004--
Pain in extremity15.03.04.010--
Pain in jaw15.02.01.003--Not Available
Palpitations02.11.04.012--
Pancreatitis07.18.01.001--
Panophthalmitis06.04.05.005--Not Available
Papule23.03.03.038--Not Available
Paraesthesia23.03.03.094; 17.02.06.005--
Pathological fracture12.04.02.006; 16.32.03.007; 15.08.02.008--Not Available
Periorbital oedema23.04.01.002; 10.01.05.010; 06.08.03.017--
Pharyngitis22.07.03.004; 11.01.13.003; 07.05.07.004--
Photophobia17.17.02.006; 06.01.01.004--
Plasma cell myeloma16.23.02.004; 01.14.02.004--Not Available
Pneumonia11.01.09.003; 22.07.01.003--Not Available
Pruritus23.03.12.001--
Pyrexia08.05.02.003--
Rash23.03.13.001--Not Available
Rash pruritic23.03.13.030--Not Available
Retinal oedema24.03.07.006; 06.04.06.007--Not Available
Rhinitis22.07.03.006; 11.01.13.004--
Rhinorrhoea22.12.03.021--
Sciatica17.10.03.001; 15.10.01.001--Not Available
Scleritis10.02.01.025; 06.04.07.002--Not Available
Shock24.06.02.002--Not Available
Sinusitis11.01.13.005; 22.07.03.007--
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