Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Risedronic acid
Drug ID BADD_D01950
Description Risedronic acid is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label][A959].
Indications and Usage Risedronic acid is indicated for the treatment of osteoperosis in men, treatment of Paget's disease, treatment and prevention of osteoperosis in postmenopausal women, and treatment and prevention of glucocorticoid-induced osteoperosis[FDA Label].
Marketing Status approved; investigational
ATC Code M05BA07
DrugBank ID DB00884
KEGG ID D08484
MeSH ID D000068296
PubChem ID 5245
TTD Drug ID D0PA5S
NDC Product Code Not Available
UNII KM2Z91756Z
Synonyms Risedronic Acid | 1-Hydroxy-2-(3-pyridyl)ethylidene diphosphonate | Atelvia | Risedronate Sodium | 2-(3-pyridinyl)-1-hydroxyethylidene-bisphosphonate | 2-(3-pyridinyl)-1-hydroxyethylidenebisphosphonate | Risedronic Acid, Monosodium Salt | Actonel | Risedronate | Bisphosphonate Risedronate Sodium | Risedronate Sodium, Bisphosphonate | Sodium, Bisphosphonate Risedronate
Chemical Information
Molecular Formula C7H11NO7P2
CAS Registry Number 105462-24-6
SMILES C1=CC(=CN=C1)CC(O)(P(=O)(O)O)P(=O)(O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Abdominal distension07.01.04.001--
Abdominal pain07.01.05.002--
Abdominal pain lower07.01.05.010--Not Available
Abdominal pain upper07.01.05.003--
Amblyopia06.02.01.001--Not Available
Anaemia01.03.02.001--
Angina pectoris24.04.04.002; 02.02.02.002--
Angioedema22.04.02.008; 23.04.01.001; 10.01.05.009--Not Available
Anorectal disorder07.03.01.001--Not Available
Anxiety19.06.02.002--
Arrhythmia02.03.02.001--Not Available
Arthralgia15.01.02.001--
Arthritis15.01.01.001--
Arthropathy15.01.01.003--Not Available
Asthenia08.01.01.001--Not Available
Asthma22.03.01.002; 10.01.03.010--Not Available
Atrial fibrillation02.03.03.002--
Back pain15.03.04.005--
Benign prostatic hyperplasia21.04.02.001--Not Available
Bladder pain20.02.02.001--Not Available
Blood parathyroid hormone increased13.10.07.002--Not Available
Body temperature increased13.15.01.001--Not Available
Bone disorder15.02.04.004--Not Available
Bone pain15.02.01.001--
Bronchitis22.07.01.001; 11.01.09.001--
Burning sensation17.02.06.001; 08.01.09.029--Not Available
Bursitis12.04.03.010; 15.04.01.001--Not Available
Cardiovascular disorder02.11.01.010; 24.03.02.009--Not Available
Cataract06.06.01.001--
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