Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Rimexolone
Drug ID BADD_D01946
Description Rimexolone is a 1% eye drop solution is a glucocorticoid steroid. It is used to treat inflammation in the eye. It is marketed as Vexol.
Indications and Usage For the treatment of postoperative inflammation following ocular surgery and in the treatment of anterior uveitis.
Marketing Status Discontinued
ATC Code H02AB12; S01BA13
DrugBank ID DB00896
KEGG ID D05729
MeSH ID C013769
PubChem ID 5311412
TTD Drug ID D0D2TN
NDC Product Code 60870-0423
Synonyms rimexolone | 11 beta-hydroxy-16 alpha,17 alpha,21-trimethylpregna-1,4-diene-3,20-dione | Rimexel | Vexol | Org 6216 | Org-6216
Chemical Information
Molecular Formula C24H34O3
CAS Registry Number 49697-38-3
SMILES CCC(=O)C1(C(CC2C1(CC(C3C2CCC4=CC(=O)C=CC34C)O)C)C)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Cataract subcapsular06.06.01.002--Not Available
Conjunctival oedema06.04.01.001--Not Available
Corneal erosion06.06.03.003--Not Available
Corneal oedema06.04.02.001--Not Available
Discomfort08.01.08.003--Not Available
Dry eye06.08.02.001--
Dysgeusia17.02.07.003; 07.14.03.001--
Eye discharge06.04.05.001--Not Available
Eye infection11.01.06.001; 06.04.05.007--
Eye pain06.08.03.002--
Fibrin increased13.01.02.026--Not Available
Headache17.14.01.001--
Herpes simplex23.09.03.001; 11.05.02.001--Not Available
Hyperaemia24.03.02.002--Not Available
Hypotension24.06.03.002--
Intraocular pressure increased13.07.04.002--Not Available
Keratitis06.04.02.002--
Lacrimation increased06.08.02.004--
Migraine24.03.05.003; 17.14.02.001--Not Available
Oedema14.05.06.010; 08.01.07.006--Not Available
Optic nerve injury12.01.16.001; 06.11.02.001; 17.04.05.008--Not Available
Pharyngitis11.01.13.003; 22.07.03.004; 07.05.07.004--
Photophobia17.17.02.006; 06.01.01.004--
Pruritus23.03.12.001--
Rhinitis22.07.03.006; 11.01.13.004--
Scab23.03.03.004--Not Available
Skin irritation23.03.04.009--Not Available
Vision blurred17.17.01.010; 06.02.06.007--
Visual acuity reduced17.17.01.011; 06.02.03.001--
Visual field defect17.17.01.001; 06.02.07.003--Not Available
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