Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Rimantadine hydrochloride
Drug ID BADD_D01945
Description An RNA synthesis inhibitor that is used as an antiviral agent in the prophylaxis and treatment of influenza.
Indications and Usage For the prophylaxis and treatment of illness caused by various strains of influenza A virus in adults.
Marketing Status Prescription; Discontinued
ATC Code J05AC02
DrugBank ID DB00478
KEGG ID D00901
MeSH ID D012299
PubChem ID 15165
TTD Drug ID D0P2NN
NDC Product Code 63629-3552; 63818-0434; 0115-1911
Synonyms Rimantadine | Remantadine | Riamantadine | Roflual | Flumadine | Rimantadine Hydrochloride | Hydrochloride, Rimantadine
Chemical Information
Molecular Formula C12H22ClN
CAS Registry Number 1501-84-4
SMILES CC(C12CC3CC(C1)CC(C3)C2)N.Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Hyperkinesia17.01.02.008--Not Available
Hypertension24.08.02.001--
Hypoaesthesia17.02.06.023--Not Available
Insomnia19.02.01.002; 17.15.03.002--
Lacrimation increased06.08.02.004--
Nausea07.01.07.001--
Nervousness19.06.02.003--Not Available
Oedema peripheral14.05.06.011; 08.01.07.007; 02.05.04.007--
Pallor24.03.04.001; 23.03.03.031; 08.01.03.032--Not Available
Palpitations02.01.02.003--
Parosmia22.04.03.007; 17.04.04.002--Not Available
Pollakiuria20.02.02.007--
Pyrexia08.05.02.003--
Rash23.03.13.001--Not Available
Seizure17.12.03.001--
Somnolence19.02.05.003; 17.02.04.006--
Stomatitis07.05.06.005--
Syncope24.06.02.012; 17.02.04.008; 02.01.02.008--
Tachycardia02.03.02.007--Not Available
Tinnitus04.04.01.002; 17.04.07.004--
Tremor17.01.06.002--
Vomiting07.01.07.003--
Decreased appetite14.03.01.005; 08.01.09.028--
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