Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Retinol
Drug ID BADD_D01930
Description Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune response. Dietary vitamin A is derived from a variety of carotenoids found in plants. It is enriched in the liver, egg yolks, and the fat component of dairy products.
Indications and Usage For the treatment of vitamin A deficiency.
Marketing Status Discontinued
ATC Code A11CA01; D10AD02; R01AX02; S01XA02
DrugBank ID DB00162
KEGG ID D06543
MeSH ID D014801
PubChem ID 445354
TTD Drug ID D0S7WX
NDC Product Code 73238-001
Synonyms Vitamin A | Aquasol A | Retinol | 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol, (all-E)-Isomer | All-Trans-Retinol | All Trans Retinol | Vitamin A1 | 11-cis-Retinol
Chemical Information
Molecular Formula C20H30O
CAS Registry Number 11103-57-4
SMILES CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CCO)C)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Blood and lymphatic system disordersThrombomodulinP07204T085839869176; 9767357; 11549653; 11919402
Blood and lymphatic system disordersvon Willebrand factorP04275T233489869176; 9767357; 11549653; 11919402
InflammationRetinol-binding protein 1P09455Not Available6685972; 6543480; 1517032
InflammationRetinol-binding protein 1P09455Not Available8725149; 9614154; 9772136
OsteodystrophyRetinol-binding protein 1P09455Not Available8725149; 9614154; 9772136
OsteodystrophyRetinol-binding protein 1P09455Not Available6685972; 6543480; 1517032
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Anaphylactic shock24.06.02.004; 10.01.07.002--Not Available
Hypersensitivity10.01.03.003--
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