Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Remifentanil hydrochloride
Drug ID BADD_D01923
Description Remifentanil (marketed by Abbott as Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and adjunctive to an anaesthetic. Remifentanil is a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and causes respiratory depression and analgesia.
Indications and Usage For use during the induction and maintenance of general anesthesia.
Marketing Status Prescription
ATC Code N01AH06
DrugBank ID DB00899
KEGG ID D01177
MeSH ID D000077208
PubChem ID 60814
TTD Drug ID D0T5OX
NDC Product Code 48954-724; 68475-506; 63323-725; 0143-9393; 63323-723; 67457-914; 50683-0550; 43798-761; 68475-507; 67457-198; 12502-5343; 67457-912; 67457-913; 0143-9391; 68475-505; 63323-724; 0143-9392
Synonyms Remifentanil | 3-(4-Methoxycarbonyl-4-((1-oxopropyl)phenylamino)-1-piperidine)propanoic Acid Methyl Ester | Remifentanil Hydrochloride | Ultiva | Remifentanil Monohydrochloride | GI 87084B | GI87084B | GI-87084B
Chemical Information
Molecular Formula C20H29ClN2O5
CAS Registry Number 132539-07-2
SMILES CCC(=O)N(C1=CC=CC=C1)C2(CCN(CC2)CCC(=O)OC)C(=O)OC.Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Confusional state19.13.01.001; 17.02.03.005--
Constipation07.02.02.001--
Cough22.02.03.001--
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Disorientation19.13.01.002; 17.02.05.015--Not Available
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Dry mouth07.06.01.002--
Dyskinesia17.01.02.006--
Dyspepsia07.01.02.001--
Dysphagia07.01.06.003--
Dysphoria19.04.02.004--Not Available
Dyspnoea22.02.01.004; 02.01.03.002--
Dysuria20.02.02.002--
Electrocardiogram abnormal13.14.05.001--Not Available
Electrolyte imbalance14.05.01.002--Not Available
Erythema23.03.06.001--Not Available
Eyelid ptosis17.17.02.004; 06.05.01.002--Not Available
Feeling abnormal08.01.09.014--Not Available
Flushing24.03.01.002; 23.06.05.003; 08.01.03.025--
Gastrooesophageal reflux disease07.02.02.003--
Gastrointestinal disorder07.11.01.001--Not Available
Haematochezia24.07.02.012; 07.12.02.003--Not Available
Haematuria24.07.01.047; 20.02.01.006--
Haemoglobin13.01.05.018--Not Available
Haemoptysis24.07.01.006; 22.02.03.004; 02.01.02.006--Not Available
Hallucination19.10.02.002--
Headache17.14.01.001--
Hepatic function abnormal09.01.02.001--Not Available
Hiccups22.02.04.002; 07.01.06.009--
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