Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Regadenoson
Drug ID BADD_D01921
Description Regadenoson is an A2A adenosine receptor agonist that causes coronary vasodilation and used for myocardial perfusion imagining. Manufactured by Astellas and FDA approved April 10, 2008.
Indications and Usage Diagnostic agent for radionuclide myocardial perfusion imaging (MPI)
Marketing Status approved; investigational
ATC Code C01EB21
DrugBank ID DB06213
KEGG ID D05711
MeSH ID C430916
PubChem ID 219024
TTD Drug ID D0XE1C
NDC Product Code 55150-443; 0409-1401; 76329-3321; 42973-229; 76055-0024; 60505-6116; 72611-874; 59285-029; 69766-103; 68083-175; 16729-477; 71288-201; 0641-6253; 65129-1331; 43598-616; 0469-6501; 62147-0220; 36000-364
UNII 2XLN4Y044H
Synonyms regadenoson | Lexiscan | CVT 3146 | CVT3146 | CVT-3146
Chemical Information
Molecular Formula C15H18N8O5
CAS Registry Number 313348-27-5
SMILES CNC(=O)C1=CN(N=C1)C2=NC(=C3C(=N2)N(C=N3)C4C(C(C(O4)CO)O)O)N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Moaning08.01.03.094; 19.04.02.0110.000085%Not Available
Muscle spasms15.05.03.0040.002097%
Muscle twitching15.05.03.0050.000169%Not Available
Musculoskeletal pain15.03.04.0070.000702%
Myalgia15.05.02.001--
Myocardial infarction24.04.04.009; 02.02.02.0070.000338%
Myocardial ischaemia02.02.02.008; 24.04.04.010--Not Available
Nausea07.01.07.0010.011553%
Nervous system disorder17.02.10.001--Not Available
Nervousness19.06.02.0030.000431%Not Available
Nodal arrhythmia02.03.03.0200.000085%Not Available
Nodal rhythm02.03.03.0210.000085%Not Available
Oral discomfort07.05.05.001--Not Available
Oxygen saturation decreased13.02.01.004--Not Available
Pain08.01.08.004--
Pain in extremity15.03.04.0100.003958%
Pain in jaw15.02.01.0030.000186%Not Available
Pallor24.03.04.001; 23.03.03.031; 08.01.03.0320.000397%Not Available
Palpitations02.11.04.012--
Paraesthesia17.02.06.005; 23.03.03.094--
Peripheral coldness08.01.09.010; 23.06.04.008; 24.04.03.006--Not Available
Presyncope02.11.04.013; 24.06.02.010; 17.02.05.0090.001446%
Rash23.03.13.001--Not Available
Rash erythematous23.03.13.0290.000186%Not Available
Renal failure20.01.03.005--Not Available
Respiratory arrest22.02.01.0090.000085%Not Available
Respiratory disorder22.02.07.0020.000330%Not Available
Respiratory distress22.02.01.0120.000254%Not Available
Retching07.01.07.0020.000186%Not Available
Seizure17.12.03.0010.002334%
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