Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Regadenoson
Drug ID BADD_D01921
Description Regadenoson is an A2A adenosine receptor agonist that causes coronary vasodilation and used for myocardial perfusion imagining. Manufactured by Astellas and FDA approved April 10, 2008.
Indications and Usage Diagnostic agent for radionuclide myocardial perfusion imaging (MPI)
Marketing Status approved; investigational
ATC Code C01EB21
DrugBank ID DB06213
KEGG ID D05711
MeSH ID C430916
PubChem ID 219024
TTD Drug ID D0XE1C
NDC Product Code 55150-443; 0409-1401; 76329-3321; 42973-229; 76055-0024; 60505-6116; 72611-874; 59285-029; 69766-103; 68083-175; 16729-477; 71288-201; 0641-6253; 65129-1331; 43598-616; 0469-6501; 62147-0220; 36000-364
UNII 2XLN4Y044H
Synonyms regadenoson | Lexiscan | CVT 3146 | CVT3146 | CVT-3146
Chemical Information
Molecular Formula C15H18N8O5
CAS Registry Number 313348-27-5
SMILES CNC(=O)C1=CN(N=C1)C2=NC(=C3C(=N2)N(C=N3)C4C(C(C(O4)CO)O)O)N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Cardiac arrest02.03.04.0010.001395%
Cardio-respiratory arrest22.02.06.007; 02.03.04.0020.000254%Not Available
Cerebrovascular accident24.03.05.001; 17.08.01.0070.000803%
Cerebrovascular disorder24.03.05.002; 17.08.02.002--Not Available
Chest discomfort08.01.08.019; 02.02.02.009; 22.12.02.0020.002267%Not Available
Chest pain22.12.02.003; 08.01.08.002; 02.02.02.0110.002782%Not Available
Chills15.05.03.016; 08.01.09.0010.000787%
Chronic obstructive pulmonary disease22.03.01.007--Not Available
Cold sweat08.01.03.024; 23.02.03.0020.000330%Not Available
Coronary artery disease24.04.04.006; 02.02.01.0010.000127%Not Available
Cough22.02.03.001--
Crying08.01.03.005; 19.04.02.002; 17.02.05.013; 12.02.11.0010.000288%Not Available
Depressed level of consciousness17.02.04.0020.000372%
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Discomfort08.01.08.0030.000846%Not Available
Dizziness17.02.05.003; 02.11.04.006; 24.06.02.0070.004136%
Dysgeusia17.02.07.003; 07.14.03.001--
Dyskinesia17.01.02.0060.000186%
Dyspnoea02.11.05.003; 22.02.01.0040.008297%
Ear disorder04.03.01.001--Not Available
Electrocardiogram QT prolonged13.14.05.004--
Electrocardiogram ST segment13.14.05.035--Not Available
Electrocardiogram ST segment depression13.14.05.005--Not Available
Erythema23.03.06.0010.001522%Not Available
Extrasystoles02.03.02.003--Not Available
Extravasation08.01.03.0080.005320%Not Available
Eye disorder06.08.03.001--Not Available
Eye pain06.08.03.002--
Eye swelling06.08.03.0030.000228%Not Available
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