Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Rasagiline mesylate
Drug ID BADD_D01916
Description Rasagiline is an irreversible inhibitor of monoamine oxidase and is used as a monotherapy in early Parkinson's disease or as an adjunct therapy in more advanced cases.
Indications and Usage For the treatment of the signs and symptoms of idiopathic Parkinsons disease as initial monotherapy and as adjunct therapy to levodopa.
Marketing Status Prescription
ATC Code N04BD02
DrugBank ID DB01367
KEGG ID D02562
MeSH ID C031967
PubChem ID 3052775
TTD Drug ID D06OMW
NDC Product Code 68546-229; 66039-878; 55111-900; 0378-1270; 57741-1900; 65015-775; 57741-2000; 43451-004; 68546-142; 23155-747; 0378-1271; 23155-746; 82245-0114; 65035-133
Synonyms rasagiline | N-2-propynyl-1-indanamine | AGN 1135 | AGN-1135 | TVP 1022 | TVP1022 | TVP-1022 | N-propargyl-1-aminoindan mesylate | rasagiline hydrochloride | TVP 101 | TVP-101 | 2,3-dihydro-N-2-propynyl-1H-inden-1-amine-(1R)-hydrochloride | Azilect
Chemical Information
Molecular Formula C13H17NO3S
CAS Registry Number 161735-79-1
SMILES CS(=O)(=O)O.C#CCNC1CCC2=CC=CC=C12
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Parosmia22.04.03.007; 17.04.04.002--Not Available
Peroneal nerve palsy17.09.02.003--Not Available
Personality disorder19.05.02.002--Not Available
Phlebitis24.05.03.001; 12.02.01.002--
Photophobia17.17.02.006; 06.01.01.004--
Photosensitivity reaction23.03.09.003--
Pleural effusion22.05.02.002--
Pneumothorax22.05.02.003--
Pollakiuria20.02.02.007--
Polyuria20.02.03.002--Not Available
Priapism21.03.01.005--Not Available
Pruritus23.03.12.001--
Pulmonary fibrosis22.01.02.006--
Purpura24.07.06.005; 01.01.04.003; 23.06.01.004--
Pyrexia08.05.02.003--
Radial nerve palsy17.09.02.004--Not Available
Rash23.03.13.001--Not Available
Rash pustular23.03.10.003; 11.01.12.002--
Retinal degeneration06.09.03.002--Not Available
Retinal detachment12.01.04.004; 06.09.03.003--
Retinal haemorrhage06.10.01.001; 24.07.05.003--Not Available
Rhinitis22.07.03.006; 11.01.13.004--
Scrotal oedema21.12.02.001--Not Available
Seizure17.12.03.001--
Serotonin syndrome17.05.02.004; 15.05.04.016; 12.03.01.041--Not Available
Sexual dysfunction21.03.02.003; 19.08.05.002--Not Available
Shock24.06.02.002--Not Available
Skin cancer23.08.02.002; 16.03.02.002--Not Available
Skin disorder23.03.03.007--Not Available
Skin ulcer24.04.03.007; 23.07.03.003--
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