Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Rasagiline mesylate
Drug ID BADD_D01916
Description Rasagiline is an irreversible inhibitor of monoamine oxidase and is used as a monotherapy in early Parkinson's disease or as an adjunct therapy in more advanced cases.
Indications and Usage For the treatment of the signs and symptoms of idiopathic Parkinsons disease as initial monotherapy and as adjunct therapy to levodopa.
Marketing Status Prescription
ATC Code N04BD02
DrugBank ID DB01367
KEGG ID D02562
MeSH ID C031967
PubChem ID 3052775
TTD Drug ID D06OMW
NDC Product Code 68546-229; 66039-878; 55111-900; 0378-1270; 57741-1900; 65015-775; 57741-2000; 43451-004; 68546-142; 23155-747; 0378-1271; 23155-746; 82245-0114; 65035-133
Synonyms rasagiline | N-2-propynyl-1-indanamine | AGN 1135 | AGN-1135 | TVP 1022 | TVP1022 | TVP-1022 | N-propargyl-1-aminoindan mesylate | rasagiline hydrochloride | TVP 101 | TVP-101 | 2,3-dihydro-N-2-propynyl-1H-inden-1-amine-(1R)-hydrochloride | Azilect
Chemical Information
Molecular Formula C13H17NO3S
CAS Registry Number 161735-79-1
SMILES CS(=O)(=O)O.C#CCNC1CCC2=CC=CC=C12
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Blepharitis23.03.04.012; 06.04.04.001--Not Available
Blindness17.17.01.003; 06.02.02.001--Not Available
Blood pressure increased13.14.03.005--Not Available
Body temperature increased13.15.01.001--Not Available
Bundle branch block02.03.01.009--Not Available
Bursitis15.04.01.001--Not Available
Cardiac failure02.05.01.001--
Carpal tunnel syndrome17.09.02.001--Not Available
Cerebral haemorrhage24.07.04.001; 17.08.01.003--Not Available
Cerebral ischaemia24.04.06.003; 17.08.01.005--
Cerebrovascular accident24.03.05.001; 17.08.01.007--
Chest pain08.01.08.002; 22.02.08.003; 02.02.02.011--Not Available
Chills15.05.03.016; 08.01.09.001--
Colitis07.08.01.001--
Compulsions19.06.05.003--Not Available
Confusional state19.13.01.001; 17.02.03.005--
Conjunctivitis11.01.06.012; 06.04.01.002--
Constipation07.02.02.001--
Coordination abnormal17.02.02.004--Not Available
Cough22.02.03.001--
Cyst16.02.02.002; 08.03.05.001--Not Available
Deafness04.02.01.001--Not Available
Delirium19.13.02.001--
Delusion19.10.01.001--
Dementia19.20.02.001; 17.03.01.001--Not Available
Depressed level of consciousness17.02.04.002--
Depression19.15.01.001--
Dermatitis23.03.04.002--Not Available
Dermatitis bullous23.03.01.002--
Dermatitis exfoliative23.03.07.001; 10.01.01.004--
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