Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Quinaprilat
Drug ID BADD_D01892
Description The active metabolite of the prodrug [quinapril].
Indications and Usage Not Available
Marketing Status experimental
ATC Code Not Available
DrugBank ID DB14217
KEGG ID D03773
MeSH ID C054501
PubChem ID 107994
TTD Drug ID Not Available
NDC Product Code Not Available
UNII 34SSX5LDE5
Synonyms quinaprilat | 2-(2-((1-carboxy-3-phenylpropyl)amino)-1-oxopropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid | quinaprilat, (3S-(2(R*(R*)),3R*))-isomer | CI 928 | CI-928
Chemical Information
Molecular Formula C23H26N2O5
CAS Registry Number 82768-85-2
SMILES CC(C(=O)N1CC2=CC=CC=C2CC1C(=O)O)NC(CCC3=CC=CC=C3)C(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Myalgia15.05.02.001--
Myocardial infarction24.04.04.009; 02.02.02.0070.010875%
Nausea07.01.07.001--
Neoplasm malignant16.16.01.0010.001813%Not Available
Nervousness19.06.02.003--Not Available
Oedema14.05.06.010; 08.01.07.006--Not Available
Oral discomfort07.05.05.0010.003988%Not Available
Orthostatic hypotension24.06.03.004; 17.05.01.020--Not Available
Palpitations02.11.04.0120.007975%
Pancreatitis07.18.01.001--
Paraesthesia17.02.06.005; 23.03.03.094--
Pemphigus23.03.01.005; 10.04.02.003--Not Available
Pharyngitis22.07.03.004; 11.01.13.003; 07.05.07.004--
Photosensitivity reaction23.03.09.003--
Pruritus23.03.12.001--
Pulmonary eosinophilia22.01.01.009; 01.02.04.006--Not Available
Rash23.03.13.0010.021569%Not Available
Renal failure20.01.03.005--Not Available
Shock24.06.02.002--Not Available
Skin lesion23.03.03.0100.001813%Not Available
Somnolence19.02.05.003; 17.02.04.006--
Swelling08.01.03.0150.015407%Not Available
Swollen tongue23.04.01.014; 10.01.05.015; 07.14.02.0030.015226%Not Available
Syncope02.11.04.015; 24.06.02.012; 17.02.04.008--
Systemic lupus erythematosus15.06.02.003; 10.04.03.004; 23.03.02.0060.003625%Not Available
Tachycardia02.03.02.007--Not Available
Tension19.06.02.005--Not Available
Thrombocytopenia01.08.01.002--Not Available
Urinary tract infection20.08.02.001; 11.01.14.004--
Urticaria10.01.06.001; 23.04.02.0010.006163%
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