Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Propoxyphene napsylate
Drug ID BADD_D01866
Description Not Available
Indications and Usage Propoxyphene is a centrally acting opiate analgesic. It is indicated for the relief of mild to moderate pain
Marketing Status Discontinued
ATC Code N02AC04
DrugBank ID DB09396
KEGG ID D05632
MeSH ID C084813
PubChem ID 28332
TTD Drug ID D03HCZ
NDC Product Code Not Available
Synonyms propoxyphene napsylate | d-propoxyphene napsylate | dextropropoxyphene napsylate
Chemical Information
Molecular Formula C32H37NO5S
CAS Registry Number 17140-78-2
SMILES CCC(=O)OC(CC1=CC=CC=C1)(C2=CC=CC=C2)C(C)CN(C)C.C1=CC=C2C=C(C=CC2=C1)S(=O)(=O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Hallucination19.10.02.002--
Headache17.14.01.001--
Hepatic steatosis14.08.04.005; 09.01.07.003--Not Available
Hepatocellular injury09.01.07.008--Not Available
Hepatomegaly09.01.05.001--Not Available
Hip fracture15.08.03.001; 12.04.01.001--
Hypersensitivity10.01.03.003--
Influenza22.07.02.001; 11.05.03.001--Not Available
Insomnia19.02.01.002; 17.15.03.002--
Metabolic acidosis14.01.01.003--Not Available
Myocardial infarction24.04.04.009; 02.02.02.007--
Nausea07.01.07.001--
Overdose12.08.01.003--Not Available
Pancreatitis acute07.18.01.002--Not Available
Pruritus23.03.12.001--
Rash23.03.13.001--Not Available
Respiratory arrest22.02.01.009--Not Available
Respiratory depression22.02.01.010; 17.02.05.047--Not Available
Sedation17.02.04.005--Not Available
Seizure17.12.03.001--
Somnolence19.02.05.003; 17.02.04.006--
Syncope24.06.02.012; 17.02.04.008; 02.01.02.008--
Tachycardia02.03.02.007--Not Available
Vision blurred17.17.01.010; 06.02.06.007--
Visual impairment06.02.06.008--Not Available
Vomiting07.01.07.003--
Mental status changes19.07.01.001--Not Available
Drug tolerance08.06.01.003--Not Available
Abnormal behaviour19.01.01.001--Not Available
Psychotic disorder19.03.01.002--
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