Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Propoxyphene napsylate
Drug ID BADD_D01866
Description Not Available
Indications and Usage Propoxyphene is a centrally acting opiate analgesic. It is indicated for the relief of mild to moderate pain
Marketing Status Discontinued
ATC Code N02AC04
DrugBank ID DB09396
KEGG ID D05632
MeSH ID C084813
PubChem ID 28332
TTD Drug ID D03HCZ
NDC Product Code Not Available
Synonyms propoxyphene napsylate | d-propoxyphene napsylate | dextropropoxyphene napsylate
Chemical Information
Molecular Formula C32H37NO5S
CAS Registry Number 17140-78-2
SMILES CCC(=O)OC(CC1=CC=CC=C1)(C2=CC=CC=C2)C(C)CN(C)C.C1=CC=C2C=C(C=CC2=C1)S(=O)(=O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Agitation19.06.02.001; 17.02.05.012--
Arrhythmia02.03.02.001--Not Available
Asthenia08.01.01.001--Not Available
Ataxia08.01.02.004; 17.02.02.001--
Bradycardia02.03.02.002--Not Available
Cardiac arrest02.03.04.001--
Cardiac failure congestive02.05.01.002--Not Available
Cardio-respiratory arrest22.02.06.007; 02.03.04.002--Not Available
Coma17.02.09.001--Not Available
Completed suicide08.04.01.010; 19.12.01.001--Not Available
Confusional state19.13.01.001; 17.02.03.005--
Constipation07.02.02.001--
Death08.04.01.001--
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Discomfort08.01.08.003--Not Available
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Drug dependence19.07.02.009--Not Available
Drug ineffective08.06.01.006--Not Available
Drug interaction08.06.03.001--Not Available
Drug withdrawal syndrome19.07.02.011; 08.06.02.004--Not Available
Dyspepsia07.01.02.001--
Dysphoria19.04.02.004--Not Available
Dyspnoea22.02.01.004; 02.01.03.002--
Euphoric mood19.04.02.006--
Eye swelling06.08.03.003--Not Available
Gastrointestinal disorder07.11.01.001--Not Available
Gastrointestinal haemorrhage24.07.02.009; 07.12.02.001--Not Available
Gastrointestinal pain07.01.05.005--
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