Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Prilocaine
Drug ID BADD_D01836
Description A local anesthetic that is similar pharmacologically to lidocaine. Currently, it is used most often for infiltration anesthesia in dentistry. (From AMA Drug Evaluations Annual, 1992, p165)
Indications and Usage Used as a local anaesthetic and is often used in dentistry.
Marketing Status approved
ATC Code N01BB04
DrugBank ID DB00750
KEGG ID D00553
MeSH ID D011318
PubChem ID 4906
TTD Drug ID D06LYG
NDC Product Code 59014-0052; 73309-214; 24196-186; 53335-0004; 69617-011; 17381-017; 52119-020; 22365-119; 49452-6011; 82891-020
UNII 046O35D44R
Synonyms Prilocaine | Propitocaine | Citanest Octapressin | Xylonest | Citanest | Prilocaine Hydrochloride
Chemical Information
Molecular Formula C13H20N2O
CAS Registry Number 721-50-6
SMILES CCCNC(C)C(=O)NC1=CC=CC=C1C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Acidosis14.01.03.002--
Anaemia01.03.02.001--
Anaphylactic shock24.06.02.004; 10.01.07.002--Not Available
Anaphylactoid reaction24.06.03.007; 10.01.07.003--Not Available
Anxiety19.06.02.002--
Arachnoiditis17.06.01.001; 12.02.04.002--
Arrhythmia02.03.02.001--Not Available
Asthenia08.01.01.001--Not Available
Blood pH decreased13.02.01.016--Not Available
Bradycardia02.03.02.002--Not Available
Brain hypoxia24.04.06.022; 22.02.02.010; 17.08.02.009--Not Available
Bronchospasm22.03.01.004; 10.01.03.012--
Cardiac arrest02.03.04.001--
Cardiac failure02.05.01.001--
Confusional state19.13.01.001; 17.02.03.005--
Cyanosis22.02.02.007; 23.06.04.005; 02.11.04.004; 24.03.01.007--
Depressed level of consciousness17.02.04.002--
Dermatitis atopic10.01.04.004; 23.03.04.016--Not Available
Diplopia17.17.01.005; 06.02.06.002--Not Available
Disorientation19.13.01.002; 17.02.05.015--Not Available
Dizziness02.11.04.006; 24.06.02.007; 17.02.05.003--
Dysarthria19.19.03.001; 17.02.08.001--
Euphoric mood19.04.02.006--
Extravasation08.01.03.008--Not Available
Feeling abnormal08.01.09.014--Not Available
Feeling hot08.01.09.009--Not Available
Haemoglobin normal13.01.05.023--Not Available
Hyperacusis04.02.02.001; 17.04.03.003--Not Available
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hypersensitivity10.01.03.003--
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