Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Prednisone
Drug ID BADD_D01834
Description A synthetic anti-inflammatory glucocorticoid derived from [cortisone].[A187463] It is biologically inert and converted to [prednisolone] in the liver.[L10502] Prednisone was granted FDA approval on 21 February 1955.[L10496]
Indications and Usage Diez JJ, Iglesias P: Pharmacological therapy of Cushing's syndrome: drugs and indications. Mini Rev Med Chem. 2007 May;7(5):467-80.
Marketing Status Prescription; Discontinued
ATC Code A07EA03; H02AB07
DrugBank ID DB00635
KEGG ID C07370
MeSH ID D011241
PubChem ID 5865
TTD Drug ID D0IL7L
NDC Product Code 51655-355; 70934-259; 60219-1705; 50090-3330; 71329-107; 80425-0069; 0527-2932; 63629-7917; 68071-2661; 61919-226; 0054-0018; 58118-0173; 50090-3336; 66267-173; 53002-3520; 59651-485; 61919-326; 42291-771; 75987-022; 71335-0464; 63629-2254; 63739-588; 70518-2676; 68071-4319; 60687-145; 67296-1183; 68071-5196; 53002-3250; 0603-5337; 53002-3092; 75987-021; 0054-8724; 51655-208; 68788-9309; 59651-489; 70954-060; 60219-1708; 69668-220; 51655-701; 66267-171; 55700-208; 63629-2264; 0527-2931; 63629-7753; 71335-1628; 64380-783; 60219-1707; 70954-057; 0591-5443; 42708-105; 66267-812; 0615-8395; 70934-218; 76420-067; 51655-726; 59746-175; 55700-209; 0527-2930; 71610-641; 50090-4428; 63629-8119; 63629-2260; 0527-2935; 53002-3252; 68071-4491; 42708-115; 0054-4742; 51407-360; 61919-235; 71335-0857; 80425-0106; 71335-1516; 67296-1419; 50090-2608; 82298-103; 50090-1990; 68071-5242; 68071-4685; 42291-769; 75987-020; 68788-8116; 68788-9551; 67296-1194; 71335-1915; 43063-866; 67544-399; 71205-407; 67296-0974; 68788-8108; 50090-4784; 70934-101; 0527-2934; 42708-136; 58118-5442; 60219-1706; 13672-031; 0591-5442; 51407-359; 63629-2261; 59651-487; 71335-0856; 63629-4562; 42291-768; 70518-1854; 63629-1587; 67296-0138; 70954-058; 55154-4949; 43063-703; 68071-2578; 68071-2304; 0054-9818; 71335-1220; 63629-2435; 70518-0306; 50090-1989; 71205-362; 71335-0623; 49999-028; 42291-770; 55700-203; 0054-8739; 61919-404; 70518-2703; 51407-355; 71335-1736; 71205-089; 68071-4903; 70518-2115; 80425-0105; 63187-243; 0054-3722; 70518-2314; 0054-9828; 68071-2445; 0395-8165; 50090-4785; 38779-0154; 63187-085; 70954-061; 50090-5657; 0143-9740; 68788-7692; 63187-037; 61919-108; 70518-2916; 50090-0439; 63629-1579; 71335-1285; 0904-6923; 61919-321; 42708-045; 0603-5336; 70882-117; 70518-0073; 68788-7281; 72189-275; 63187-807; 70954-059; 70518-1120; 67296-1203; 50090-1001; 50090-5814; 63629-2257; 60760-615; 67296-1065; 55154-4946; 59651-486; 67296-1083; 71335-0508; 68071-3143; 0143-9739; 50090-5660; 70934-831; 51552-0028; 63629-2259; 71335-1926; 60687-122; 70934-137; 64380-782; 43063-911; 0378-0640; 67296-1704; 55289-330; 71335-0651; 68071-2594; 50090-5656; 50090-0098; 71335-1780; 67296-0140; 50090-2532; 68071-5195; 0054-4728; 63629-2263; 50090-2786; 72189-246; 50090-3137; 42708-114; 54348-506; 68071-2500; 71329-105; 0615-0536; 0054-0019; 70518-2704; 71335-1524; 70934-096; 0904-7127; 68071-2209; 63187-997; 53002-3091; 71335-1629; 71335-1737; 63629-2258; 0527-2933; 55154-8130; 59651-484; 42291-727; 50090-0102; 51407-357; 59746-173; 68788-7637; 71335-0335; 0615-8307; 68071-2511; 68071-4862; 70934-699; 59746-172; 70934-674; 67296-1331; 68071-4691; 60760-255; 50090-1455; 71335-1525; 71205-460; 76420-068; 61919-373; 63629-2262; 59651-488; 0603-5339; 51407-358; 0603-5338; 76420-069; 70934-095; 68788-7752; 50090-3361; 0378-0642; 50090-1991; 71335-2051; 59746-171; 53002-0610; 0054-8740; 63187-020; 0615-3593; 67296-1755; 0603-5335; 72789-235; 0615-8306; 70518-3401; 71205-537; 70518-3138; 0615-8391; 64380-785; 60760-002; 70954-056; 57582-003; 68788-7372; 63187-300; 55154-4950; 68071-4850; 68071-2509; 0054-9817; 71205-239; 50090-5202; 0054-0017; 68071-1777; 55154-4938; 13672-033; 0591-5052; 71205-421; 71329-104; 61919-365; 45865-638; 0378-0641; 64380-835; 71329-108; 0143-9738; 70518-1561; 64380-784; 50090-5453; 71329-106; 60760-932; 70518-2138; 70518-3142; 63629-2255; 63629-2256; 13672-032; 60687-134; 63187-066; 63629-1605; 64958-0002; 50090-2789; 60760-715; 68788-6440; 50090-0097; 53002-3090; 70518-2675; 68071-1779; 66267-860; 66267-172; 43063-968; 63629-2434; 50090-5816; 71205-403; 43353-657; 51407-356; 0054-4741; 63629-8015; 67296-1767; 68788-8166; 67296-0247; 60722-1002; 45865-670; 70518-0307; 70518-0305; 71329-103; 49452-6000
Synonyms Prednisone | Dehydrocortisone | delta-Cortisone | Rectodelt | Prednison Hexal | Sterapred | Ultracorten | Winpred | Apo-Prednisone | Cortan | Cortancyl | Panafcort | Cutason | Decortin | Dacortin | Decortisyl | Deltasone | Encortone | Encorton | Enkortolon | Kortancyl | Liquid Pred | Meticorten | Orasone | Panasol | Predni Tablinen | Prednidib | Predniment | Prednison Acsis | Acsis, Prednison | Pronisone | Sone | Prednison Galen
Chemical Information
Molecular Formula C21H26O5
CAS Registry Number 53-03-2
SMILES CC12CC(=O)C3C(C1CCC2(C(=O)CO)O)CCC4=CC(=O)C=CC34C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Preterm premature rupture of membranes18.02.02.0160.000080%Not Available
Invasive ductal breast carcinoma21.05.01.021; 16.10.01.0130.000040%Not Available
Abdominal lymphadenopathy07.11.01.018; 01.09.01.0200.000040%Not Available
Large intestinal stenosis07.13.03.0040.000100%
Pseudomonas aeruginosa meningitis17.06.10.006; 11.02.12.0060.000026%Not Available
Herpes simplex oesophagitis12.02.03.020; 11.05.02.026; 07.19.06.0060.000080%Not Available
Herpes zoster meningoencephalitis17.06.06.005; 11.05.02.0300.000060%Not Available
Varicella zoster pneumonia11.05.02.034; 22.07.05.0100.000080%Not Available
Herpes zoster cutaneous disseminated23.09.03.013; 11.05.02.0270.000026%Not Available
Phospholipidosis14.08.04.0250.000040%Not Available
Graft versus host disease in gastrointestinal tract07.11.01.027; 12.02.09.028; 10.02.01.0590.000010%Not Available
Soft tissue sarcoma16.33.01.003; 15.09.03.0210.000021%Not Available
Gastrointestinal wall thickening07.01.06.0320.000080%Not Available
Macular detachment06.09.03.0200.000040%Not Available
Fine motor skill dysfunction17.01.02.0200.000060%Not Available
Steatohepatitis14.08.04.020; 09.01.07.0240.000080%Not Available
Hyperosmolar hyperglycaemic state14.07.04.006; 05.07.04.006; 17.02.04.0200.000139%Not Available
Gluten sensitivity14.02.01.008; 10.01.01.031; 07.17.01.0090.000060%Not Available
Hyperinsulinaemic hypoglycaemia14.06.03.010; 05.06.03.0100.000080%Not Available
Non-cirrhotic portal hypertension24.08.06.003; 09.01.06.0190.000060%Not Available
End stage renal disease20.01.03.0190.000199%Not Available
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