| ADR Ontology |
| ADR Term |
Herpes zoster meningoencephalitis |
| ADR ID |
BADD_A09229 |
| ADR Hierarchy |
|
| Description |
Inflammation of brain tissue caused by infection with the varicella-zoster virus (HERPESVIRUS 3, HUMAN). This condition is associated with immunocompromised states, including the ACQUIRED IMMUNODEFICIENCY SYNDROME. Pathologically, the virus tends to induce a vasculopathy and infect oligodendrocytes and ependymal cells, leading to CEREBRAL INFARCTION, multifocal regions of demyelination, and periventricular necrosis. Manifestations of varicella encephalitis usually occur 5-7 days after onset of HERPES ZOSTER and include HEADACHE; VOMITING; lethargy; focal neurologic deficits; FEVER; and COMA. (From Joynt, Clinical Neurology, 1996, Ch 26, pp29-32; Hum Pathol 1996 Sep;27(9):927-38) [MeSH] |
| MedDRA Code |
10074248 |
| MeSH ID |
D020804; D020804; D020804
|
|
ADR Severity Grade (FAERS)
|
|
|
ADR Severity Grade (CTCAE)
|
Not Available
|
| Synonym |
| Herpes zoster meningoencephalitis | Varicella zoster encephalitis | Encephalitis, Varicella Zoster | Zoster Encephalitis, Varicella | Herpes Zoster Encephalitis | Zoster Encephalitis, Herpes | Varicella Zoster Encephalitis | Encephalitis, Herpes Zoster | Encephalitis, Varicella | Encephalitis, VZ Virus | Virus Encephalitis, VZ | Encephalitis, Human Herpesvirus 3 | Varicella Encephalitis | Varicella Encephalitides | Meningoencephalitis, Herpes Zoster | Herpes Zoster Meningoencephalitis |
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| ADR Related Proteins |
| Protein Name |
UniProt AC |
TTD Target ID |
| Not Available | Not Available | Not Available |
|
| Drugs Leading to the ADR |
| Drug ID | Drug Name | ADR Frequency (FAERS) | ADR Severity Grade (FAERS) | | BADD_D01834 | Prednisone | 0.000060% | | | BADD_D02464 | Fingolimod | 0.001737% | |
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