Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Praziquantel
Drug ID BADD_D01826
Description An anthelmintic used in most schistosome and many cestode infestations.
Indications and Usage For the treatment of infections due to all species of schistosoma.
Marketing Status Prescription
ATC Code P02BA01
DrugBank ID DB01058
KEGG ID D00471
MeSH ID D011223
PubChem ID 4891
TTD Drug ID D0L9ZR
NDC Product Code 69011-0001; 86055-0003; 13371-321; 49452-5976; 38779-0090; 53104-7567; 71052-203; 12527-2521; 72643-005; 51927-2737; 14639-0022; 49884-231; 52562-022; 10745-0422; 50419-747; 62991-2053; 49169-1027
Synonyms Praziquantel | Prasiquantel | Praziquantel, (+-)-Isomer | Praziquantel, (R)-Isomer | Praziquantel, (S)-Isomer | Drontsit | Traziquantel | Biltricide | Cesol | Cysticide | Cisticid | Droncit | EMBAY 8440 | Pyquiton
Chemical Information
Molecular Formula C19H24N2O2
CAS Registry Number 55268-74-1
SMILES C1CCC(CC1)C(=O)N2CC3C4=CC=CC=C4CCN3C(=O)C2
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Oesophageal varices haemorrhage24.07.02.022; 07.12.01.003; 09.01.06.0040.007503%
Photosensitivity reaction23.03.09.0030.007503%
Polyserositis08.01.05.003--Not Available
Portal hypertension09.01.06.006; 24.08.06.0010.011254%
Portal vein thrombosis24.01.03.003; 09.01.06.0070.007503%
Pruritus23.03.12.0010.007503%
Pyrexia08.05.02.0030.022508%
Rash23.03.13.0010.011254%Not Available
Seizure17.12.03.001--
Skin disorder23.03.03.007--Not Available
Somnolence19.02.05.003; 17.02.04.006--
Splenomegaly01.09.02.0010.007503%Not Available
Syncope24.06.02.012; 17.02.04.008; 02.01.02.0080.007503%
Urticaria23.04.02.001; 10.01.06.0010.015006%
Ventricular fibrillation02.03.04.008--
Vertigo17.02.12.002; 04.04.01.003--
Vomiting07.01.07.0030.011254%
Acute generalised exanthematous pustulosis23.03.10.002; 12.03.01.0050.007503%Not Available
Musculoskeletal discomfort15.03.04.001--Not Available
Cardiac disorder02.01.01.003--Not Available
Decreased appetite14.03.01.005; 08.01.09.028--
Ill-defined disorder08.01.03.049--Not Available
Schistosomiasis20.08.02.012; 11.08.04.001; 07.19.02.0190.022508%Not Available
Portal fibrosis24.08.06.004; 09.01.04.0080.007503%Not Available
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