Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Pomalidomide
Drug ID BADD_D01798
Description Pomalidomide, an analogue of thalidomide, is an immunomodulatory antineoplastic agent. FDA approved on February 8, 2013.
Indications and Usage Pomalidomide is indicated for patients with multiple myeloma who have received at least two prior therapies including lenalidomide and bortezomib and have demonstrated disease progression on or within 60 days of completion of the last therapy.
Marketing Status approved
ATC Code L04AX06
DrugBank ID DB08910
KEGG ID D08976
MeSH ID C467566
PubChem ID 134780
TTD Drug ID D0A3ZU
NDC Product Code 65015-893; 17337-0068; 63069-404; 68554-0092; 70225-1106; 59572-501; 59572-502; 55111-989; 68554-0091; 82245-0108; 63069-402; 42973-232; 54893-0038; 59572-503; 59572-504; 63069-403
UNII D2UX06XLB5
Synonyms pomalidomide | CC-4047 | CC 4047 | CC4047 | Imnovid | Pomalyst | actimid
Chemical Information
Molecular Formula C13H11N3O4
CAS Registry Number 19171-19-8
SMILES C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Nail discolouration23.02.05.0010.002869%
Nasopharyngitis22.07.03.002; 11.01.13.002--Not Available
Nausea07.01.07.001--
Neoplasm16.16.02.0010.003400%Not Available
Nephropathy20.05.03.0010.002074%Not Available
Nerve compression17.09.02.002; 12.01.12.0010.003183%Not Available
Nervous system disorder17.02.10.001--Not Available
Nervousness19.06.02.0030.020012%Not Available
Neuralgia17.02.07.0050.010922%
Neuropathic arthropathy14.07.04.011; 05.07.04.011; 17.09.03.008; 15.01.04.0080.000651%Not Available
Neuropathy peripheral17.09.03.0030.108694%Not Available
Neutropenia01.02.03.0040.101412%Not Available
Neutrophil count decreased13.01.06.010--
Night sweats23.02.03.006; 08.01.03.0310.010344%Not Available
Nipple pain21.05.05.0090.001760%Not Available
Oedema peripheral14.05.06.011; 08.01.07.007; 02.05.04.0070.037155%
Oesophageal stenosis07.13.02.0010.000241%
Oral mucosal blistering07.05.05.0170.002990%Not Available
Osteolysis15.02.03.008; 14.04.04.0060.001254%Not Available
Pain08.01.08.004--
Pain in extremity15.03.04.010--
Pancytopenia01.03.03.0030.013117%Not Available
Papule23.03.03.0380.006679%Not Available
Paraplegia17.01.04.0070.000603%Not Available
Pathological fracture16.32.03.007; 15.08.02.008; 12.04.02.0060.001688%Not Available
Pelvic pain21.10.01.001; 20.02.03.007; 07.01.06.012--
Pelvic venous thrombosis24.01.02.0080.000362%Not Available
Penile haemorrhage24.07.03.018; 21.12.01.0110.000241%Not Available
Peripheral coldness23.06.04.008; 08.01.09.010; 24.04.03.006--Not Available
Peripheral sensory neuropathy17.09.03.005--
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