Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Pomalidomide
Drug ID BADD_D01798
Description Pomalidomide, an analogue of thalidomide, is an immunomodulatory antineoplastic agent. FDA approved on February 8, 2013.
Indications and Usage Pomalidomide is indicated for patients with multiple myeloma who have received at least two prior therapies including lenalidomide and bortezomib and have demonstrated disease progression on or within 60 days of completion of the last therapy.
Marketing Status Prescription
ATC Code L04AX06
DrugBank ID DB08910
KEGG ID D08976
MeSH ID C467566
PubChem ID 134780
TTD Drug ID D0A3ZU
NDC Product Code 59572-504; 59572-503; 68554-0091; 82245-0108; 55111-989; 17337-0068; 65015-893; 68554-0092; 42973-232; 70225-1106; 54893-0038; 59572-501; 59572-502
Synonyms pomalidomide | CC-4047 | CC 4047 | CC4047 | Imnovid | Pomalyst | actimid
Chemical Information
Molecular Formula C13H11N3O4
CAS Registry Number 19171-19-8
SMILES C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)N
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Bone pain15.02.01.0010.027792%
Bradycardia02.03.02.002--Not Available
Breast cancer21.05.01.003; 16.10.01.001--Not Available
Breast pain21.05.05.003--
Breath odour07.01.06.0020.001158%Not Available
Bronchitis22.07.01.001; 11.01.09.0010.083375%
Bronchospasm22.03.01.004; 10.01.03.012--
Burning sensation17.02.06.001; 08.01.09.029--Not Available
Bursitis15.04.01.001--Not Available
C-reactive protein increased13.09.01.007--Not Available
Cachexia14.03.02.001; 08.01.01.009; 16.32.03.0110.000604%Not Available
Cardiac amyloidosis10.02.05.002; 02.04.02.0100.000906%Not Available
Cardiac arrest02.03.04.001--
Cardiac failure02.05.01.001--
Cardiac failure acute02.05.01.005--Not Available
Cardiac failure congestive02.05.01.002--Not Available
Cardio-respiratory arrest22.02.06.007; 02.03.04.002--Not Available
Cardiogenic shock24.06.02.006; 02.05.01.003--Not Available
Cardiomegaly02.04.02.001--Not Available
Cardiomyopathy02.04.01.001--Not Available
Cardiovascular disorder24.03.02.009; 02.01.01.001--Not Available
Cataract06.06.01.0010.022581%
Cellulitis23.09.01.001; 11.02.01.0010.026055%Not Available
Cerebral haemorrhage24.07.04.001; 17.08.01.003--Not Available
Cerebral infarction24.04.06.002; 17.08.01.004--Not Available
Cerebral ischaemia17.08.01.005; 24.04.06.003--
Cerebral thrombosis24.01.04.003; 17.08.01.0060.001737%Not Available
Cerebrovascular accident24.03.05.001; 17.08.01.007--
Change of bowel habit07.02.03.0020.001158%Not Available
Chest discomfort22.02.08.001; 08.01.08.019; 02.02.02.009--Not Available
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