Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Pomalidomide
Drug ID BADD_D01798
Description Pomalidomide, an analogue of thalidomide, is an immunomodulatory antineoplastic agent. FDA approved on February 8, 2013.
Indications and Usage Pomalidomide is indicated for patients with multiple myeloma who have received at least two prior therapies including lenalidomide and bortezomib and have demonstrated disease progression on or within 60 days of completion of the last therapy.
Marketing Status Prescription
ATC Code L04AX06
DrugBank ID DB08910
KEGG ID D08976
MeSH ID C467566
PubChem ID 134780
TTD Drug ID D0A3ZU
NDC Product Code 59572-504; 59572-503; 68554-0091; 82245-0108; 55111-989; 17337-0068; 65015-893; 68554-0092; 42973-232; 70225-1106; 54893-0038; 59572-501; 59572-502
Synonyms pomalidomide | CC-4047 | CC 4047 | CC4047 | Imnovid | Pomalyst | actimid
Chemical Information
Molecular Formula C13H11N3O4
CAS Registry Number 19171-19-8
SMILES C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)N
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Blood bilirubin increased13.03.01.008--
Blood calcium abnormal13.11.01.0220.002316%Not Available
Blood calcium decreased13.11.01.002--Not Available
Blood calcium increased13.11.01.0030.011580%Not Available
Blood cholesterol increased13.12.01.002--
Blood creatinine abnormal13.13.01.0020.003474%Not Available
Blood creatinine decreased13.13.01.0030.001737%Not Available
Blood creatinine increased13.13.01.004--
Blood glucose abnormal13.02.02.0080.006948%Not Available
Blood glucose decreased13.02.02.0010.006369%Not Available
Blood glucose increased13.02.02.002--Not Available
Blood immunoglobulin G decreased13.06.05.0010.002316%Not Available
Blood immunoglobulin G increased13.06.05.0040.002895%Not Available
Blood iron decreased13.11.01.0060.004053%Not Available
Blood lactate dehydrogenase increased13.04.02.002--
Blood magnesium decreased13.11.01.0080.008685%Not Available
Blood potassium abnormal13.11.01.0240.001158%Not Available
Blood potassium decreased13.11.01.0100.016791%Not Available
Blood potassium increased13.11.01.0110.008685%Not Available
Blood pressure abnormal13.14.03.0010.012738%Not Available
Blood pressure decreased13.14.03.002--Not Available
Blood pressure fluctuation24.06.01.002--Not Available
Blood pressure increased13.14.03.005--Not Available
Blood sodium decreased13.11.01.012--Not Available
Blood triglycerides increased13.12.03.001--Not Available
Blood urea abnormal13.13.01.0050.001158%Not Available
Blood urea increased13.13.01.006--Not Available
Body temperature increased13.15.01.0010.006369%Not Available
Bone disorder15.02.04.004--Not Available
Bone neoplasm16.29.01.001; 15.09.02.0010.001158%Not Available
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