| Pharmaceutical Information |
| Drug Name |
Podofilox |
| Drug ID |
BADD_D01790 |
| Description |
A lignan found in podophyllin resin from the roots of podophyllum plants. It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts and keratoses, and may have antineoplastic properties, as do some of its congeners and derivatives. |
| Indications and Usage |
For treatment of external genital warts (Condyloma acuminatum). |
| Marketing Status |
approved |
| ATC Code |
D06BB04 |
| DrugBank ID |
DB01179
|
| KEGG ID |
D05529
|
| MeSH ID |
D011034
|
| PubChem ID |
10607
|
| TTD Drug ID |
D0D4HN
|
| NDC Product Code |
0574-0611; 63629-8832; 0591-3204; 67430-100; 0023-6118; 66245-001 |
| UNII |
L36H50F353
|
| Synonyms |
Podophyllotoxin | Podofilox | Condylox | CPH86 | Epipodophyllotoxin | Podocon-25 | Podophyllotoxin, (5R-(5 alpha,5a alpha,8a alpha,9 beta))-Isomer | Podophyllotoxin, (5R-(5 alpha,5a alpha,8a beta,9 alpha))-Isomer | Podophyllotoxin, (5R-(5 alpha,5a beta,8a alpha,9 beta))-Isomer | Wartec | Warticon | Podofilm | Condyline | Podophyllotoxin, (5R-(5 alpha,5a alpha,8a alpha,9 alpha))-Isomer |
|
| Chemical Information |
| Molecular Formula |
C22H22O8 |
| CAS Registry Number |
518-28-5 |
| SMILES |
COC1=CC(=CC(=C1OC)OC)C2C3C(COC3=O)C(C4=CC5=C(C=C24)OCO5)O |
| Chemical Structure |
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| ADRs Induced by Drug |
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