Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Perphenazine
Drug ID BADD_D01743
Description An antipsychotic phenothiazine derivative with actions and uses similar to those of chlorpromazine.
Indications and Usage For use in the management of the manifestations of psychotic disorders and for the control of severe nausea and vomiting in adults.
Marketing Status Prescription; Discontinued
ATC Code N05AB03
DrugBank ID DB00850
KEGG ID D00503
MeSH ID D010546
PubChem ID 4748
TTD Drug ID D02HED
NDC Product Code 70518-3033; 70518-0940; 52536-164; 70518-1125; 0591-4103; 0591-4102; 0781-8046; 0591-4104; 63629-2251; 70518-0710; 0781-8047; 0603-5062; 68084-602; 63629-2250; 52536-168; 0781-8048; 68382-594; 70518-2639; 0603-5060; 70518-2985; 0904-6600; 64980-293; 65372-1191; 70771-1043; 68084-607; 52536-170; 70518-3018; 0603-5061; 70518-2890; 0904-6601; 63629-2248; 0591-4101; 64980-292; 70518-0458; 0603-5063; 70518-0731; 63629-2253; 70771-1044; 68382-592; 70518-3108; 70518-3106; 70518-1109; 70771-1041; 63629-2252; 70518-3257; 64980-290; 70518-1739; 68382-591; 63629-2249; 46204-0003; 70518-3121; 63629-7252; 52536-162; 68382-593; 53808-1124; 0781-8049; 42973-165; 64980-291; 70518-1133; 70771-1042; 0904-6599
Synonyms Perphenazine | Perfenazine | Chlorpiprazine | Trilafon
Chemical Information
Molecular Formula C21H26ClN3OS
CAS Registry Number 58-39-9
SMILES C1CN(CCN1CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)Cl)CCO
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Faecalith07.01.03.007--Not Available
Urine output increased13.13.03.002--Not Available
Libido disorder21.03.02.006; 19.08.03.004--Not Available
Lactation disorder21.05.02.004; 18.06.02.003--
Decreased appetite14.03.01.005; 08.01.09.028--
Blood disorder01.05.01.004--Not Available
Epinephrine abnormal13.10.01.003--Not Available
Psychotic disorder19.03.01.002--
Pigmentation disorder23.05.03.001--Not Available
Liver injury12.01.02.003; 09.01.07.022--Not Available
Oropharyngeal discomfort22.02.05.027; 07.05.05.008--Not Available
Oropharyngeal pain22.02.05.022; 07.05.05.004--
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