Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Perphenazine
Drug ID BADD_D01743
Description An antipsychotic phenothiazine derivative with actions and uses similar to those of chlorpromazine.
Indications and Usage For use in the management of the manifestations of psychotic disorders and for the control of severe nausea and vomiting in adults.
Marketing Status Prescription; Discontinued
ATC Code N05AB03
DrugBank ID DB00850
KEGG ID D00503
MeSH ID D010546
PubChem ID 4748
TTD Drug ID D02HED
NDC Product Code 70518-3033; 70518-0940; 52536-164; 70518-1125; 0591-4103; 0591-4102; 0781-8046; 0591-4104; 63629-2251; 70518-0710; 0781-8047; 0603-5062; 68084-602; 63629-2250; 52536-168; 0781-8048; 68382-594; 70518-2639; 0603-5060; 70518-2985; 0904-6600; 64980-293; 65372-1191; 70771-1043; 68084-607; 52536-170; 70518-3018; 0603-5061; 70518-2890; 0904-6601; 63629-2248; 0591-4101; 64980-292; 70518-0458; 0603-5063; 70518-0731; 63629-2253; 70771-1044; 68382-592; 70518-3108; 70518-3106; 70518-1109; 70771-1041; 63629-2252; 70518-3257; 64980-290; 70518-1739; 68382-591; 63629-2249; 46204-0003; 70518-3121; 63629-7252; 52536-162; 68382-593; 53808-1124; 0781-8049; 42973-165; 64980-291; 70518-1133; 70771-1042; 0904-6599
Synonyms Perphenazine | Perfenazine | Chlorpiprazine | Trilafon
Chemical Information
Molecular Formula C21H26ClN3OS
CAS Registry Number 58-39-9
SMILES C1CN(CCN1CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)Cl)CCO
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Dysphagia07.01.06.003--
Dyspnoea02.01.03.002; 22.02.01.004--
Dystonia17.01.03.001--Not Available
Eczema23.03.04.006--
Ejaculation delayed21.03.01.001--Not Available
Eosinophilia01.02.04.001--
Erythema23.03.06.001--Not Available
Extrapyramidal disorder17.01.02.007--
Galactorrhoea05.03.04.002; 21.05.02.002--Not Available
Glaucoma06.03.01.002--
Glossodynia07.14.02.001--Not Available
Glycosuria20.02.01.005--
Gynaecomastia21.05.04.003; 05.05.02.003--
Haemolytic anaemia01.06.03.002--Not Available
Headache17.14.01.001--
Heart rate abnormal13.14.04.006--Not Available
Hepatitis A11.05.06.003; 09.01.09.004--Not Available
Hepatocellular injury09.01.07.008--Not Available
Hyperglycaemia14.06.02.002; 05.06.02.002--
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hyperkinesia17.01.02.008--Not Available
Hyperphagia19.09.01.005; 14.03.01.007; 07.01.06.018--Not Available
Hyperpyrexia08.05.02.002--Not Available
Hyperreflexia17.02.01.002--Not Available
Hypersensitivity10.01.03.003--
Hypertension24.08.02.001--
Hypoaesthesia17.02.06.023--Not Available
Hypoglycaemia14.06.03.001; 05.06.03.001--
Hypotension24.06.03.002--
Ileus paralytic07.02.05.001--Not Available
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