Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Perhexiline
Drug ID BADD_D01737
Description Perhexiline is a coronary vasodilator used especially for angina of effort. It may cause neuropathy and hepatitis.
Indications and Usage For the management of severe angina pectoris.
Marketing Status Not Available
ATC Code C08EX02
DrugBank ID DB01074
KEGG ID D08340
MeSH ID D010480
PubChem ID 4746
TTD Drug ID D00SBN
NDC Product Code Not Available
Synonyms Perhexiline | Perhexilene
Chemical Information
Molecular Formula C19H35N
CAS Registry Number 39648-47-0
SMILES C1CCC(CC1)C(CC2CCCCN2)C3CCCCC3
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Asthenia08.01.01.001--Not Available
Ataxia17.02.02.001; 08.01.02.004--
Blood triglycerides increased13.12.03.001--Not Available
Cachexia16.32.03.011; 14.03.02.001; 08.01.01.009--Not Available
Dermatitis23.03.04.002--Not Available
Diplopia17.17.01.005; 06.02.06.002--Not Available
Dizziness17.02.05.003; 02.01.02.004; 24.06.02.007--
Extrapyramidal disorder17.01.02.007--
Fatigue08.01.01.002--
Flushing24.03.01.002; 23.06.05.003; 08.01.03.025--
Gait disturbance17.02.05.016; 08.01.02.002--
Gastrointestinal pain07.01.05.005--
Headache17.14.01.001--
Hepatitis09.01.07.004--Not Available
Hepatitis viral11.05.04.011; 09.01.09.007--
Hepatocellular injury09.01.07.008--Not Available
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hypertriglyceridaemia14.08.02.001--
Hypoglycaemia14.06.03.001; 05.06.03.001--
Insomnia19.02.01.002; 17.15.03.002--
Loss of consciousness17.02.04.004--Not Available
Muscular weakness17.05.03.005; 15.05.06.001--
Nausea07.01.07.001--
Nervousness19.06.02.003--Not Available
Neuropathy peripheral17.09.03.003--Not Available
Optic neuritis17.04.05.001; 10.04.10.002; 06.04.08.002--Not Available
Papilloedema24.03.07.001; 17.07.02.004; 06.09.02.002--
Paraesthesia17.02.06.005--
Polyneuropathy17.09.03.012--Not Available
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