| Pharmaceutical Information |
| Drug Name |
Perampanel |
| Drug ID |
BADD_D01733 |
| Description |
Perampanel is a noncompetitive AMPA glutamate receptor antagonist. It is marketed under the name Fycompa™ and is indicated as an adjunct in patients over 12 years old for the treatment of partial-onset seizures that may or may not occur with generalized seizures. The FDA label includes an important black-boxed warning of serious or life-threatening behavioral and psychiatric reactions in patients taking Fycompa™. |
| Indications and Usage |
Used in patients over 12 years old for the treatment of partial-onset seizures that may or may not occur with generalized seizures. |
| Marketing Status |
Prescription |
| ATC Code |
N03AX22 |
| DrugBank ID |
DB08883
|
| KEGG ID |
D08964
|
| MeSH ID |
C551441
|
| PubChem ID |
9924495
|
| TTD Drug ID |
D0U3ED
|
| NDC Product Code |
62856-278; 62856-272; 50379-0020; 62856-276; 67835-0026; 60510-609; 11071-907; 11071-906; 11071-905; 60510-606; 11071-902; 62856-274; 60510-605; 11071-904; 60510-608; 60510-604; 47848-049; 62856-280; 62856-282; 60510-607; 11071-903; 62856-290 |
| Synonyms |
perampanel | 3-(2-cyanophenyl)-5-(2-pyridyl)-1-phenyl-1,2-dihydropyridin-2-one | perampanel hydrate | perampanel hydrate (4:3) | E-2007 | E2007 | ER-155055-90 | Fycompa |
|
| Chemical Information |
| Molecular Formula |
C23H15N3O |
| CAS Registry Number |
380917-97-5 |
| SMILES |
C1=CC=C(C=C1)N2C=C(C=C(C2=O)C3=CC=CC=C3C#N)C4=CC=CC=N4 |
| Chemical Structure |
|
|
| ADR Related Proteins Induced by Drug |
| ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
| Not Available | Not Available | Not Available | Not Available | Not Available |
|
| ADRs Induced by Drug |
|
|
