| Pharmaceutical Information |
| Drug Name |
Pentostatin |
| Drug ID |
BADD_D01730 |
| Description |
A potent inhibitor of adenosine deaminase. The drug is effective in the treatment of many lymphoproliferative malignancies, particularly hairy-cell leukemia. It is also synergistic with some other antineoplastic agents and has immunosuppressive activity. |
| Indications and Usage |
For the treatment of hairy cell leukaemia refractory to alpha interferon. |
| Marketing Status |
Prescription |
| ATC Code |
L01XX08 |
| DrugBank ID |
DB00552
|
| KEGG ID |
D00155
|
| MeSH ID |
D015649
|
| PubChem ID |
439693
|
| TTD Drug ID |
D0T3AD
|
| NDC Product Code |
14096-124; 42533-109; 59981-005; 0409-0801 |
| Synonyms |
Pentostatin | Deoxycoformycin | Imidazo(4,5-d)(1,3)diazepin-8-ol, 3-(2-deoxy-beta-D-erythro-pentofuranosyl)-3,4,7,8-tetrahydro-, (R)- | 2'-Deoxycoformycin | 2' Deoxycoformycin | NSC-218321 | NSC 218321 | NSC218321 | Co-Vidarabine | CI-825 | CI 825 | CI825 | Nipent |
|
| Chemical Information |
| Molecular Formula |
C11H16N4O4 |
| CAS Registry Number |
53910-25-1 |
| SMILES |
C1C(C(OC1N2C=NC3=C2NC=NCC3O)CO)O |
| Chemical Structure |
|
|
| ADR Related Proteins Induced by Drug |
| ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
| Not Available | Not Available | Not Available | Not Available | Not Available |
|
| ADRs Induced by Drug |
|
|
