Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Pentosan polysulfate
Drug ID BADD_D01728
Description Pentosan polysulfate is a sulfated pentosyl polysaccharide with heparin-like properties.
Indications and Usage For the relief of bladder pain or discomfort associated with interstitial cystitis.
Marketing Status Prescription
ATC Code C05BA04; G04BX15
DrugBank ID DB00686
KEGG ID D05428
MeSH ID D010426
PubChem ID 37720
TTD Drug ID D0F8CM
NDC Product Code Not Available
Synonyms Pentosan Sulfuric Polyester | Polyester, Pentosan Sulfuric | Sulfuric Polyester, Pentosan | Pentosane Sulfuric Polyester | Polyester, Pentosane Sulfuric | Sulfuric Polyester, Pentosane | Xylan Sulfate | Sulfate, Xylan | Polypentose Sulfate | Sulfate, Polypentose | Polysulfated Xylan | Xylan, Polysulfated | Fibrocid | Hemoclar | HOE-BAY-946 | HOE BAY 946 | HOE-BAY 946 | BAY-946 | BAY 946 | HOE-946 | HOE 946 | Xylan SP54 | SP54, Xylan | Pentosan Polysulphate Sodium | Polysulphate Sodium, Pentosan | Sodium, Pentosan Polysulphate | Pentosan Polysulfate Sodium | Polysulfate Sodium, Pentosan | Sodium, Pentosan Polysulfate | PZ-68 | PZ 68 | PZ68 | SP-54 | SP 54 | SP54 | Tavan SP 54 | SP 54, Tavan | Elmiron | Pentosan Polysulfate | Polysulfate, Pentosan
Chemical Information
Molecular Formula C10H18O21S4
CAS Registry Number 37300-21-3
SMILES C1C(C(C(C(O1)OC2COC(C(C2OS(=O)(=O)O)OS(=O)(=O)O)O)OS(=O)(=O)O)OS(=O)(=O)O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Gingival bleeding24.07.02.010; 07.09.07.001--Not Available
Haematochezia24.07.02.012; 07.12.02.0030.000571%Not Available
Haematuria24.07.01.047; 20.02.01.006--
Headache17.14.01.001--
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hyperkinesia17.01.02.008--Not Available
Hypersensitivity10.01.03.003--
Infection11.01.08.002--Not Available
Insomnia19.02.01.002; 17.15.03.002--
Jaundice01.06.04.004; 23.03.03.030; 09.01.01.004--Not Available
Lacrimation increased06.08.02.004--
Leukopenia01.02.02.001--Not Available
Liver function test abnormal13.03.01.013--Not Available
Maculopathy06.09.03.0070.017137%Not Available
Malaise08.01.01.0030.000857%
Menorrhagia21.01.03.002--
Micturition urgency20.02.02.006--
Mood swings19.04.03.001--Not Available
Mouth ulceration07.05.06.004--Not Available
Myalgia15.05.02.001--
Nausea07.01.07.001--
Nystagmus17.02.02.006; 06.05.02.006--
Oedema14.05.06.010; 08.01.07.006--Not Available
Oesophagitis07.08.05.001--
Optic neuritis17.04.05.001; 10.04.10.002; 06.04.08.002--Not Available
Pain08.01.08.0040.001428%
Paraesthesia17.02.06.005--
Pelvic pain21.10.01.001; 20.02.03.007; 07.01.06.012--
Pharyngitis07.05.07.004; 22.07.03.004; 11.01.13.003--
Photosensitivity reaction23.03.09.003--
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