Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Pentazocine lactate
Drug ID BADD_D01720
Description The first mixed agonist-antagonist analgesic to be marketed. It is an agonist at the kappa and sigma opioid receptors and has a weak antagonist action at the mu receptor. (From AMA Drug Evaluations Annual, 1991, p97)
Indications and Usage For the relief of moderate to severe pain.
Marketing Status approved; vet_approved
ATC Code N02AD01
DrugBank ID DB00652
KEGG ID D02111
MeSH ID D010423
PubChem ID 656697
TTD Drug ID D0W6DG
NDC Product Code 48087-0007
UNII 1P2XIB510O
Synonyms Pentazocine | Lexir | Pentazocine Lactate | Lactate, Pentazocine | Talwin | Fortral | Pentazocine Hydrochloride | Hydrochloride, Pentazocine
Chemical Information
Molecular Formula C22H33NO4
CAS Registry Number 17146-95-1
SMILES CC1C2CC3=C(C1(CCN2CC=C(C)C)C)C=C(C=C3)O.CC(C(=O)O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abnormal dreams19.02.03.001; 17.15.02.001--Not Available
Agitation19.06.02.001; 17.02.05.012--
Anaphylactoid reaction24.06.03.007; 10.01.07.003--Not Available
Anxiety19.06.02.002--
Apnoea22.02.01.001--
Asthenia08.01.01.001--Not Available
Ataxia17.02.02.001; 08.01.02.004--
Chest discomfort22.12.02.002; 08.01.08.019; 02.02.02.009--Not Available
Chills15.05.03.016; 08.01.09.001--
Cold sweat23.02.03.002; 08.01.03.024--Not Available
Confusional state19.13.01.001; 17.02.03.005--
Constipation07.02.02.001--
Cyanosis23.06.04.005; 02.11.04.004; 24.03.01.007; 22.02.02.007--
Depression19.15.01.001--
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Diplopia17.17.01.005; 06.02.06.002--Not Available
Disorientation19.13.01.002; 17.02.05.015--Not Available
Dizziness17.02.05.003; 02.11.04.006; 24.06.02.007--
Drug dependence19.07.06.011--Not Available
Drug interaction08.06.03.001--Not Available
Dry mouth07.06.01.002--
Dysarthria19.19.03.001; 17.02.08.001--
Dysgeusia17.02.07.003; 07.14.03.001--
Dysphonia22.12.03.006; 19.19.03.002; 17.02.08.004--
Dyspnoea02.11.05.003; 22.02.01.004--
Eosinophilia01.02.04.001--
Euphoric mood19.04.02.006--
Face oedema10.01.05.002; 08.01.07.003; 23.04.01.004--
Fear19.06.03.001--Not Available
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