Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Pentazocine lactate
Drug ID BADD_D01720
Description The first mixed agonist-antagonist analgesic to be marketed. It is an agonist at the kappa and sigma opioid receptors and has a weak antagonist action at the mu receptor. (From AMA Drug Evaluations Annual, 1991, p97)
Indications and Usage For the relief of moderate to severe pain.
Marketing Status Discontinued; Prescription
ATC Code N02AD01
DrugBank ID DB00652
KEGG ID D02111
MeSH ID D010423
PubChem ID 656697
TTD Drug ID D0W6DG
NDC Product Code 48087-0007
Synonyms Pentazocine | Lexir | Pentazocine Lactate | Lactate, Pentazocine | Talwin | Fortral | Pentazocine Hydrochloride | Hydrochloride, Pentazocine
Chemical Information
Molecular Formula C22H33NO4
CAS Registry Number 17146-95-1
SMILES CC1C2CC3=C(C1(CCN2CC=C(C)C)C)C=C(C=C3)O.CC(C(=O)O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abnormal dreams19.02.03.001; 17.15.02.001--Not Available
Agitation19.06.02.001; 17.02.05.012--
Apnoea22.02.01.001--
Asthenia08.01.01.001--Not Available
Chills08.01.09.001; 15.05.03.016--
Confusional state19.13.01.001; 17.02.03.005--
Constipation07.02.02.001--
Depression19.15.01.001--
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Diplopia06.02.06.002; 17.17.01.005--Not Available
Disorientation19.13.01.002; 17.02.05.015--Not Available
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Dry mouth07.06.01.002--
Dysgeusia07.14.03.001; 17.02.07.003--
Dyspnoea22.02.01.004; 02.01.03.002--
Eosinophilia01.02.04.001--
Euphoric mood19.04.02.006--
Face oedema10.01.05.002; 08.01.07.003; 23.04.01.004--
Flushing24.03.01.002; 23.06.05.003; 08.01.03.025--
Granulocytes abnormal13.01.06.034--Not Available
Hallucination19.10.02.002--
Headache17.14.01.001--
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hypersensitivity10.01.03.003--
Hypertension24.08.02.001--
Injection site pain12.07.03.011; 08.02.03.010--Not Available
Insomnia17.15.03.002; 19.02.01.002--
Irritability19.04.02.013; 08.01.03.011--
Miosis17.02.11.002; 06.05.03.003--Not Available
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