Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Patiromer
Drug ID BADD_D01686
Description Patiromer is a powder for suspension in water for oral administration, approved in the U.S. as Veltassa in October, 2015. Patiromer is supplied as patiromer sorbitex calcium which consists of the active moiety, patiromer, a non-absorbed potassium-binding polymer, and a calcium-sorbitol counterion. Each gram of patiromer is equivalent to a nominal amount of 2 grams of patiromer sorbitex calcium. The chemical name for patiromer sorbitex calcium is cross-linked polymer of calcium 2-fluoroprop-2-enoate with diethenylbenzene and octa-1,7-diene, combination with D-glucitol. Patiromer sorbitex calcium is an amorphous, free-flowing powder that is composed of individual spherical beads.
Indications and Usage For the treatment of hyperkalemia.
Marketing Status Prescription
ATC Code V03AE09
DrugBank ID DB09263
KEGG ID D11037
MeSH ID C568789
PubChem ID Not Available
TTD Drug ID D0Z2YQ
NDC Product Code 53436-252; 53436-084; 53436-168
Synonyms patiromer | Veltassa | RLY 5016 | RLY5016 | RLY-5016
Chemical Information
Molecular Formula Not Available
CAS Registry Number 1260643-52-4
SMILES Not Available
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Unresponsive to stimuli17.02.05.031-Not Available
Urinary retention20.02.02.011-
Urinary tract infection20.08.02.001; 11.01.14.004--
Urticaria23.04.02.001; 10.01.06.001--
Vision blurred17.17.01.010; 06.02.06.007--
Vomiting07.01.07.003-
Weight decreased13.15.01.005--
Mental status changes19.07.01.001-Not Available
Peripheral swelling08.01.03.053; 02.05.04.015-Not Available
Abasia17.02.05.035; 08.01.02.007-Not Available
Blood phosphorus decreased13.11.01.015-Not Available
Blood phosphorus increased13.11.01.016-Not Available
Faecaloma07.01.03.004-Not Available
Cardiac disorder02.01.01.003-Not Available
Feeding disorder14.03.02.003; 19.09.01.003-Not Available
Upper limb fracture15.08.03.018; 12.04.01.018-Not Available
Decreased appetite14.03.01.005; 08.01.09.028--
Ill-defined disorder08.01.03.049-Not Available
Lower limb fracture15.08.03.004; 12.04.01.004-Not Available
Drug intolerance08.06.01.013--Not Available
Obstruction08.01.03.023-Not Available
Renal impairment20.01.03.010-Not Available
Respiratory tract infection11.01.08.017; 22.07.07.001-Not Available
Unevaluable event08.01.03.051-Not Available
Bowel movement irregularity07.02.03.003-Not Available
Chronic kidney disease20.01.03.017-
Oral herpes07.05.07.002; 11.05.02.005-Not Available
Acute kidney injury20.01.03.016--
Anal incontinence17.05.01.021; 07.01.06.029-
Blood creatine decreased13.13.01.026-Not Available
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