Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Patiromer
Drug ID BADD_D01686
Description Patiromer is a powder for suspension in water for oral administration, approved in the U.S. as Veltassa in October, 2015. Patiromer is supplied as patiromer sorbitex calcium which consists of the active moiety, patiromer, a non-absorbed potassium-binding polymer, and a calcium-sorbitol counterion. Each gram of patiromer is equivalent to a nominal amount of 2 grams of patiromer sorbitex calcium. The chemical name for patiromer sorbitex calcium is cross-linked polymer of calcium 2-fluoroprop-2-enoate with diethenylbenzene and octa-1,7-diene, combination with D-glucitol. Patiromer sorbitex calcium is an amorphous, free-flowing powder that is composed of individual spherical beads.
Indications and Usage For the treatment of hyperkalemia.
Marketing Status Prescription
ATC Code V03AE09
DrugBank ID DB09263
KEGG ID D11037
MeSH ID C568789
PubChem ID Not Available
TTD Drug ID D0Z2YQ
NDC Product Code 53436-252; 53436-084; 53436-168
Synonyms patiromer | Veltassa | RLY 5016 | RLY5016 | RLY-5016
Chemical Information
Molecular Formula Not Available
CAS Registry Number 1260643-52-4
SMILES Not Available
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Neoplasm malignant16.16.01.001--Not Available
Nephrolithiasis20.04.01.002-
Nephropathy20.05.03.001-Not Available
Oedema peripheral14.05.06.011; 08.01.07.007; 02.05.04.007--
Osteomyelitis15.02.05.001; 11.01.01.001-
Pain08.01.08.004--
Palpitations02.01.02.003--
Paralysis17.01.04.004-Not Available
Petechiae24.07.06.004; 23.06.01.003; 01.01.03.002-Not Available
Pneumonia22.07.01.003; 11.01.09.003--Not Available
Pollakiuria20.02.02.007-
Pruritus23.03.12.001--
Pulmonary oedema22.01.03.003; 02.05.02.003-
Rash23.03.13.001--Not Available
Rash generalised23.03.13.002-Not Available
Rectal haemorrhage24.07.02.018; 07.12.03.001-
Renal disorder20.01.02.002-Not Available
Renal failure20.01.03.005-Not Available
Respiratory disorder22.02.07.002-Not Available
Respiratory distress22.02.01.012-Not Available
Respiratory failure22.02.06.002; 14.01.04.003--
Retching07.01.07.002-Not Available
Seizure17.12.03.001--
Sepsis11.01.11.003-
Small intestinal obstruction07.13.06.001-
Swelling08.01.03.015--Not Available
Swelling face23.04.01.018; 10.01.05.018-Not Available
Swollen tongue07.14.02.003; 23.04.01.014; 10.01.05.015-Not Available
Thrombosis24.01.01.006--Not Available
Tremor17.01.06.002--
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