Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Paricalcitol
Drug ID BADD_D01676
Description Paricalcitol is a synthetic vitamin D analog. Paricalcitol has been used to reduce parathyroid hormone levels. Paricalcitol is indicated for the prevention and treatment of secondary hyperparathyroidism associated with chronic renal failure.
Indications and Usage For treatment of secondary hyperparathyroidism associated with chronic kidney disease (CKD) Stage 3 and 4
Marketing Status approved; investigational
ATC Code H05BX02
DrugBank ID DB00910
KEGG ID D00930
MeSH ID C084656
PubChem ID 5281104
TTD Drug ID D0N1TP
NDC Product Code 0074-1658; 0074-4637; 0074-9036; 0143-9624; 65162-823; 65862-936; 70121-1035; 43598-565; 55150-213; 67457-379; 66499-0019; 16729-311; 43598-562; 55150-215; 68382-331; 65862-938; 67457-692; 69452-147; 10888-8103; 10888-8104; 11014-0334; 48943-0033; 58032-1001; 68513-1054; 49483-689; 55150-212; 68382-330; 69452-145; 70121-1033; 70121-1034; 10888-8102; 14474-021; 0143-9625; 49483-687; 65862-937; 11014-0048; 55111-663; 70121-1036; 58272-192; 0074-9037; 43598-563; 49483-688; 55111-665; 63629-2452; 67457-380; 16729-310; 25000-017; 0143-9596; 55150-214; 63629-2453; 65162-822; 67457-389; 69452-146; 25000-014; 43598-564; 55111-664; 65162-824; 11014-0053; 25000-012
UNII 6702D36OG5
Synonyms paricalcitol | 19-nor-1alpha,25-dihydroxyvitamin D2 | 19-nor-1,25-(OH)2D2 | Zemplar | paricalcitol-d6
Chemical Information
Molecular Formula C27H44O3
CAS Registry Number 131918-61-1
SMILES CC(C=CC(C)C(C)(C)O)C1CCC2C1(CCCC2=CC=C3CC(CC(C3)O)O)C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Stupor19.02.05.004; 17.02.04.007--Not Available
Sudden death02.03.04.013; 08.04.01.0030.030412%
Swelling08.01.03.015--Not Available
Syncope02.11.04.015; 24.06.02.012; 17.02.04.008--
Tension19.06.02.005--Not Available
Thirst08.01.09.021; 14.03.02.007--Not Available
Unresponsive to stimuli17.02.05.031--Not Available
Upper respiratory tract infection22.07.03.011; 11.01.13.009--
Urethral disorder20.07.01.002--Not Available
Urinary tract disorder20.08.01.001--Not Available
Urinary tract infection11.01.14.004; 20.08.02.001--
Urticaria23.04.02.001; 10.01.06.001--
Uterine cancer21.07.02.003; 16.12.05.0010.002943%Not Available
Vaginal infection21.14.02.002; 11.01.10.002--
Vertigo04.04.01.003; 17.02.12.002--
Viral infection11.05.04.001--Not Available
Vomiting07.01.07.003--
Weight decreased13.15.01.005--
Wheezing22.03.01.009--
Myocardial haemorrhage24.07.01.035; 02.04.02.0180.002943%Not Available
Ischaemic cardiomyopathy24.04.04.019; 02.04.01.0040.007848%Not Available
Brain death17.02.03.003; 08.04.01.0040.002943%Not Available
Sudden cardiac death08.04.01.008; 02.03.04.0160.001962%Not Available
Tachyarrhythmia02.03.02.0080.002943%Not Available
Cardiac death08.04.01.007; 02.03.04.0150.001962%Not Available
Cardiopulmonary failure22.02.06.004; 02.05.01.0040.002943%Not Available
Calciphylaxis14.04.01.0120.003924%Not Available
Haemodynamic instability24.03.02.0060.003924%Not Available
Ear discomfort04.03.01.005--Not Available
Respiratory tract congestion22.02.07.0030.001962%Not Available
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ADReCS-Target
Drug Name ADR Term Target
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