| Drug Name |
Parathyroid hormone |
| Drug ID |
BADD_D01673 |
| Description |
Parathyroid hormone (PTH) is a single-chain polypeptide composed of 84 amino acids. Available as Preotact, it is an identical form of human recombinant hormome which produced as a fusion protein undergoeing post-translational processing involving the cleavage of the OmpA leader sequence, leaving the mature protein as a single-chain 84 amino-acids polypeptide (9.4 kDa).
Preotact is used in the treatment of osteoporosis in postmenopausal women at high risk of osteoporotic fractures and is marketed in Europe by Nycomed. Preos is a registered trade mark owned by NPS Pharmaceuticals, Inc. The name Preos and the New Drug Application is pending approval by the U.S. Food and Drug Administration (FDA). |
| Indications and Usage |
For use/treatment in osteoporosis. |
| Marketing Status |
approved; investigational |
| ATC Code |
H05AA03 |
| DrugBank ID |
DB05829
|
| KEGG ID |
D05364
|
| MeSH ID |
D010281
|
| PubChem ID |
Not Available
|
| TTD Drug ID |
D04PRM
|
| NDC Product Code |
68875-0204; 68875-0202; 68875-0203; 68875-0205 |
| UNII |
N19A0T0E5J
|
| Synonyms |
Parathyroid Hormone | Hormone, Parathyroid | PTH (1-84) | Parathyroid Hormone (1-84) | Parathormone | Parathyrin | Parathyroid Hormone Peptide (1-34) | Parathyroid Hormone (1-34) | PTH(1-34) | Natpara |
