Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Parathyroid hormone
Drug ID BADD_D01673
Description Parathyroid hormone (PTH) is a single-chain polypeptide composed of 84 amino acids. Available as Preotact, it is an identical form of human recombinant hormome which produced as a fusion protein undergoeing post-translational processing involving the cleavage of the OmpA leader sequence, leaving the mature protein as a single-chain 84 amino-acids polypeptide (9.4 kDa). Preotact is used in the treatment of osteoporosis in postmenopausal women at high risk of osteoporotic fractures and is marketed in Europe by Nycomed. Preos is a registered trade mark owned by NPS Pharmaceuticals, Inc. The name Preos and the New Drug Application is pending approval by the U.S. Food and Drug Administration (FDA).
Indications and Usage For use/treatment in osteoporosis.
Marketing Status Prescription
ATC Code H05AA03
DrugBank ID DB05829
KEGG ID D05364
MeSH ID D010281
PubChem ID Not Available
TTD Drug ID D04PRM
NDC Product Code 68875-0203; 68875-0205; 68875-0202; 68875-0204
Synonyms Parathyroid Hormone | Hormone, Parathyroid | PTH (1-84) | Parathyroid Hormone (1-84) | Parathormone | Parathyrin | Parathyroid Hormone Peptide (1-34) | Parathyroid Hormone (1-34) | PTH(1-34) | Natpara
Chemical Information
Molecular Formula Not Available
CAS Registry Number 9002-64-6
SMILES Not Available
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain upper07.01.05.003--
Arthralgia15.01.02.001--
Blood calcium13.11.01.041--Not Available
Diarrhoea07.02.01.001--
Headache17.14.01.001--
Hypercalcaemia14.04.01.003; 05.04.01.002--
Hypercalciuria20.02.01.007; 14.04.01.006; 05.04.01.003--Not Available
Hypertension24.08.02.001--
Hypoaesthesia17.02.06.023--Not Available
Hypocalcaemia14.04.01.004--
Nausea07.01.07.001--
Neck pain15.03.04.009--
Osteosarcoma16.29.03.002; 15.09.03.010--Not Available
Pain in extremity15.03.04.010--
Paraesthesia17.02.06.005--
Sinusitis22.07.03.007; 11.01.13.005--
Upper respiratory tract infection22.07.03.011; 11.01.13.009--
Vomiting07.01.07.003--
Blood 25-hydroxycholecalciferol decreased13.02.05.009--Not Available
Antibody test13.06.03.009--Not Available
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