Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Pancrelipase
Drug ID BADD_D01664
Description Pancrelipase, in general, is composed of a mixture of pancreatic enzymes which include amylases, lipases, and proteases. These enzymes are extracted from porcine pancreatic glands.[L2509] The pancrelipase mixture was developed by Ortho-McNeil-Janssen Pharmaceuticals, Inc and FDA approved on April 12, 2010.[L2510] For further information on the components of this mixture please visit [DB11065], [DB11066] and [DB13147].
Indications and Usage Not Available
Marketing Status Prescription
ATC Code Not Available
DrugBank ID DB00085
KEGG ID D05349
MeSH ID D020799
PubChem ID 8519
TTD Drug ID D0A5DJ
NDC Product Code 31387-219; 54809-1026; 54809-1024; 58914-117; 57298-805; 54809-9048; 59767-024; 81618-0003; 73562-104; 0032-1224; 31387-165; 57298-802; 54809-3823; 0032-1206; 58914-112; 0032-3016; 73562-208; 59767-016; 57298-807; 54809-1025; 57298-806; 59767-004; 59767-008; 57298-804; 0032-1212; 31387-137; 31387-205; 57298-803; 0032-1203
Synonyms Pancrelipase | Cotazyme | Creon | Encron | Ilozyme | Ku-Zyme | Ku Zyme | Lipram | Pancrease | Pancrecarb | Pancron | Panokase | Pertzye | Protilase | Ultrase | Viokase | Zymase | Cotazym-S | Cotazym S
Chemical Information
Molecular Formula C8H8Na2O5
CAS Registry Number 129-67-9
SMILES C1CC2C(C(C1O2)C(=O)[O-])C(=O)[O-].[Na+].[Na+]
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Anaphylactic reaction24.06.03.006; 10.01.07.001--
Asthma22.03.01.002; 10.01.03.010--Not Available
Constipation07.02.02.001--
Cough22.02.03.001--
Diarrhoea07.02.01.001--
Dyspepsia07.01.02.001--
Flatulence07.01.04.002--
Gastrointestinal disorder07.11.01.001--Not Available
Headache17.14.01.001--
Hypersensitivity10.01.03.003--
Nausea07.01.07.001--
Neoplasm malignant16.16.01.001--Not Available
Pruritus23.03.12.001--
Rash23.03.13.001--Not Available
Rash macular23.03.13.003--Not Available
Skin disorder23.03.03.007--Not Available
Urticaria23.04.02.001; 10.01.06.001--
Fibrosing colonopathy07.13.03.002--Not Available
Distal intestinal obstruction syndrome07.13.01.006--Not Available
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