Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Oxycodone
Drug ID BADD_D01645
Description Oxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917.[A178696] It is currently indicated as an immediate release product for moderate to severe pain and as an extended release product for chronic moderate to severe pain requiring continuous opioid analgesics for an extended period.[Label] The first oxycodone containing product, Percodan, was approved by the FDA on April 12, 1950.[L6460]
Indications and Usage For the treatment of diarrhoea, pulmonary oedema and for the relief of moderate to moderately severe pain.
Marketing Status Prescription; Discontinued
ATC Code N02AA05
DrugBank ID DB00497
KEGG ID D05312
MeSH ID D010098
PubChem ID 5284603
TTD Drug ID D07WPQ
NDC Product Code 68071-5055; 0904-7180; 65162-047; 24510-115; 24510-130; 67651-0304; 65162-050; 71335-1023; 67651-0306; 67651-0305; 71335-0981; 24510-140; 71335-1080; 65162-051; 24510-120; 65162-048; 67877-625; 71335-0677; 65162-049; 67651-0303; 24510-110; 67877-623; 0904-6966; 67651-0302
Synonyms Oxycodone | Dihydrone | Oxycone | Dihydrohydroxycodeinone | Oxycodeinon | Eucodal | Theocodin | Oxycodone Hydrochloride | Oxycontin | Pancodine | Dinarkon | Oxiconum
Chemical Information
Molecular Formula C18H21NO4
CAS Registry Number 76-42-6
SMILES CN1CCC23C4C(=O)CCC2(C1CC5=C3C(=C(C=C5)OC)O4)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Hiatus hernia22.09.02.004; 07.16.01.0010.000139%Not Available
Hiccups07.01.06.009; 22.02.04.0020.000093%
Hip fracture15.08.03.001; 12.04.01.0010.000186%
Hydrocephalus17.07.01.0010.000186%
Hyperaesthesia17.02.06.0040.000279%Not Available
Hypercalcaemia14.04.01.003; 05.04.01.002--
Hypercapnia22.02.02.002; 14.01.04.0010.000186%Not Available
Hyperglycaemia14.06.02.002; 05.06.02.002--
Hyperhidrosis23.02.03.004; 08.01.03.0280.001439%
Hyperkalaemia14.05.03.001--
Hyperkinesia17.01.02.008--Not Available
Hyperpyrexia08.05.02.0020.000093%Not Available
Hypersensitivity10.01.03.003--
Hypersomnia17.15.01.001; 19.02.05.0010.000139%
Hypertension24.08.02.001--
Hypertonia17.05.02.001; 15.05.04.0070.000093%Not Available
Hyperventilation22.02.01.006; 19.01.02.004--Not Available
Hypoaesthesia17.02.06.023--Not Available
Hypocalcaemia14.04.01.0040.000464%
Hypoglycaemia14.06.03.001; 05.06.03.001--
Hypokinesia17.01.02.0090.000186%Not Available
Hyponatraemia14.05.04.002--
Hypopnoea22.02.01.0210.000093%Not Available
Hypotension24.06.03.002--
Hypothermia12.05.03.001; 08.05.01.003--
Hypotonia17.05.02.002; 15.05.04.008--Not Available
Hypoxia22.02.02.0030.000789%
Ileus07.13.01.0010.000232%
Ileus paralytic07.02.05.0010.000139%Not Available
Immune system disorder10.02.01.001--Not Available
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